Current Concepts of Bone Fragility

Skeleton as an Organ of Physical Support.- Basic Biomechanics of the Skeleton.- Biomechanical Factors in Adaptation of Bone Structure to Function.- Cellular Mechanisms Underlying the Skeleton’s Supportive Function.- Diagnostic and Monitoring Tools.- Diagnosis and Follow-up of Patients with Osteoporosis.- Modern Imaging of Patients with Metabolic Bone Disease.- Nuclear Medicine Applications to Metabolic Bone Disease.- Quantitative Assessment of Bone: Radiologic Methods.- Bone Turnover Assessment Using Bone-Specific Biochemical Markers.- The Role of Bone Biopsy in Metabolic Bone Disease.- Bone Microdamage: Factors That Impair Its Repair.- Loads versus Bone Strength.- Impaired Bone Strength and Fracture Patterns at Different Skeletal Sites.- Fracture Patterns in Children.- Cortical Porosity in Postmenopausal and Adolescent Wrist Fractures.- Pathologic Fractures and Stress Fractures: A Review of Pathogenesis and Assessment.- Disuse Osteoporosis: Current Status and Problems.- Osteoporosis: Limitations of Strain-Related Bone Remodeling in Its Prevention.- Disorganized Bone Structure.- Congenital Osteopetrosis.- Osteogenesis Imperfecta: Current Concepts.- Setpoint Proposal for Osteogenesis Imperfecta.- Osteogenesis Imperfecta: Orthopedic Aspects.- Paget’s Disease of Bone (Osteitis deformans).- Paget’s Disease of Bone: Orthopedic Management.- Reversible Osteopenias.- Bone Fragility in Osteomalacia: Mechanism and Consequences.- Drug-Induced Osteomalacia.- Accelerated Cortical Bone Loss: Primary and Secondary Hyperparathyroidism.- Skeletal Problems in Chronic Renal Diseases.- Glucocorticoid-Induced Osteoporosis.- Etiological Spectrum of Avascular Necrosis.- Reversible Osteopenia: Orthopedic Aspects.- Osteoporosis.- Pathogenic Mechanisms of the Osteoporoses.- Morphology of Bone Tissue Aging.- Biomechanical Compensatory Mechanisms for Age-Related Changes in Cortical Bone.- Hip Fracture and Cortical Bone Density in Aging African and Caucasian Populations.- Hip Fracture: A Disease and an Accident.- Economic and Social Burden of Osteoporosis.- Involutional Osteoporosis. Critical Evaluation of Medical Treatments.- Repetitive Loading to Prevent Osteoporosis in the Vertebral Column.- Orthopedic Management of Osteoporosis: Effects of Nutrition and Exercise on the Skeleton.