Framed for the brutal murders of his classmates by the mysterious Red Man, middle school student Ganta Igarashi finds himself sentenced to death and sent to the bizarre and fatal theme park/prison that has risen from the ruins of the Great Tokyo Earthquake - a hell on earth known as Deadman Wonderland.

The residents of G Ward have won their battle with the Ko Unit but have been badly injured by the intense fighting. Meanwhile, Ganta gathers what strength he has left and joins Makina. Together they head for the top level of Deadman Wonderland to attempt to deliver the Endae Faust - the Final Fist - that will put an end to the insane plans of promoter Tamaki. But what they find waiting for them may lead to even more despair…