This collection of papers aims to increase our understanding of a) what meaning in life is: how it is to be understood, what its constituents are, and how it can be properly distinguished from other features that are commonly thought to be required for a good life, such as happiness, b) in what way, if any, mortality can be said to be detrimental to a life's meaningfulness and what follows from this for the desirability of radical life extension and other (limit-removing) alterations of the present human condition, and c) in what way, if any, death and mortality can be said to be requisites or at least constituents of a meaningful life.