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Deep Brain Stimulation and Epilepsy

Autor Hans O. Lüders
en Limba Engleză Hardback – 14 noi 2003
Deep brain stimulation has been used effectively for many years to treat patients suffering from Parkinson's disease. Now, neurologists and neurosurgeons are using electric pulse generators to block abnormal activity, i.e. epileptic fits. Promising research results indicate that electric pulses implanted deep in the brain can affect neurocircuitry and help stop oncoming seizures. Supplying a solid background on brain stimulation and its application to epilepsy, Deep Brain Stimulation and Epilepsy provides a historical overview, explores pathogenesis of brain stimulation, discusses animal experiments and human studies, and explores future prospects of brain stimulation for epileptic control. The editor and his team of contributors distill information drawn directly from the literature into one convenient resource.
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Specificații

ISBN-13: 9781841842592
ISBN-10: 1841842591
Pagini: 384
Dimensiuni: 191 x 254 x 23 mm
Greutate: 0.93 kg
Ediția:1
Editura: CRC Press
Colecția CRC Press
Locul publicării:Boca Raton, United States

Public țintă

Professional

Cuprins

Historical Overview: Brain Stimulation and Epilepsy. Pathogenesis of Brain Stimulation: Animal Studies. The Basal Ganglia: Overview. Anatomy and Neurophysiology of the Subthalamic Nucleus (STN). Electrical Stimulus Characteristics. Electrically Excitable Nerve-elements. Epileptiform Activity Disrupted by Electrical Stimulation. The Nigral Control of Epilepsy (NCE) System. Effect of Repetitive Cortical Stimulation in Animals. Pathogenesis of Brain Stimulation: Human Studies. Cortico-cortical Evoked Potentials in Humans. Repetitive Transcranial Magnetic Stimulation in Humans. High Frequency STN Stimulation. Cortical Evoked Potentials to STN Stimulation. Recording of EEG from STN in Patients with Epilepsy. Recording of EEG from the ATN in Patients with Epilepsy.Effect of Brain Stimulation on Epileptic Seizures: Animal Experiments. Absence Seizures in the GAERS Model (STN Stimulation). Focal Limbic Seizures Induced by Kainic Acid (STN stimulation). Focal Cortical Dysplasia Model (STN Stimulation). Amygdaloid Kindled Model (STN). Penthyleneterazol Model (ATN Stimulation). Effect of Brain Stimulation on Epileptic Seizures: Human Studies. Vagal Nerve Stimulation. Mechanisms of Action. Surgical Technique. Effect on Seizures. Transcranial Magnetic Stimulation. Cortical Electrical Stimulation. Hippocampal Stimulation. AT Stimulation. Surgical Procedure. Study Protocol. STN Stimulation. Surgical Procedure. Preliminary Results: Grenoble Experience. Preliminary Results: Cleveland Experience. Future Developments.

Recenzii

"…Much of the data summarized in this book is not readily available elsewhere. This is a welcome addition for anyone interested in electrophysiology, epilepsy, and the therapeutic effects of electrical impulses."
-Journal of Neurosurgery
'This is the definitive account of the state of play of deep brain stimulation in epilepsy. It is a scholarly work, and covers the entire body of knowledge in this area, both in terms of animal and human studies. It is likely to be the definitive text in this specialised area.' - Highly Commended, Neurology Category, 2004 BMA Medical Book Competition
'This is a welcome addition for anyone interested in electrophysiology, epilepsy, and the therapeutic effects of electrical impulses.' - British Journal of Neurosurgery, Volume 102, June 2005

Descriere

Deep brain stimulation has been used effectively for many years in patients suffering from Parkinson's disease. Now, neurologists and neurosurgeons are using electric pulse generators (somewhat like a cardiac pacemaker) to block abnormal activity, i.e. epileptic fits. With promising research results that show how electric pulses implanted deep in the brain can affect neurocircuitry and help stop oncoming seizures, the author and his team of contributors have summarized all the available literature into one volume. Deep Brain Stimulation and Epilepsy should provide the epileptologist and neurosurgeon with a solid background about deep brain stimulation and its application to epilepsy.