Marcus Ambler is prepared for the greatest hunting trip of his life. Accompanied by his sister Cassie and Best friend Cody, he is bound for the small rural town of Sakoran in Ontario and the beautiful lake that borders it - all in hopes of bagging that "prize buck." However, it's not long after their arrival that the three notice a pattern of violent behavior among the local deer population, and this pattern soon moves farther south with deadlier results. As authorities scramble to cover up the destruction, Marcus and the others find themselves caught in a battle for their lives against the attacking creatures, as well as in a personal war between an obsessed hunter and the mysterious force behind these events. Can the humans stop this uprising, or will the deer reign supreme when the struggle is over?