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Detection Challenges in Clinical Diagnostics de Pankaj Vadgama

Detection Challenges in Clinical Diagnostics: Detection Science, cartea 02

Editat de Pankaj Vadgama, Serban Peteu
en Limba Engleză Hardback – 25 sep 2013
There are many remaining challenges impeding future progress in field of Clinical Diagnostics. This book presents a technical assessment and vision of clinical leaders, scoping the clinical and other diagnostic needs and the bottle-necks in their cognate fields.
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Specificații

ISBN-13: 9781849736121
ISBN-10: 184973612X
Pagini: 246
Dimensiuni: 163 x 238 x 20 mm
Greutate: 0.55 kg
Editura: Royal Society Of Chemistry
Seriile RSC Detection Science, Detection Science

Textul de pe ultima copertă

There are many remaining challenges impeding future progress in field of Clinical Diagnostics. This book presents a technical assessment and vision of clinical leaders, scoping the clinical and other diagnostic needs and the bottle-necks in their cognate fields. Issues of real environmental biological measurements from the perspective of the end-user are presented and thus the book serves to inform the direction of the fundamental scientific efforts. Both editors are experienced practitioners within the biosensor technology and are involved first-hand with the healthcare and clinical applications of detection science.

Cuprins

Introduction; Sensitive detection as an interface process; Improved ion-, gas- and bio-sensors; Long term implantable sensors; Ultrasensitive Protein microarrays; Monitoring nitro-oxidative stress; Nano-bio-interface diagnostics; Discussion and conclusions

Notă biografică

Professor Pankaj Vadgama's particular interest is biosensors, where he has developed permselective, biocompatible, and biomimetic polymeric membranes capable of stable transduction in whole blood and tissue. Both in vivo and in vitro work has been undertaken, including the use of miniaturized devices for glucose and lactate monitoring, immunosensing, and interrogation of tissue-material interactions. Current research work includes interfacial problems relating to sensor/biomaterial contact with the biomatrix, and the generalizable insights that may emerge from this. Projects include: spider silk for tissue engineering, materials for implantable electronic devices, microfluidic based separation, cell-surface interactions, biomaterial degradation dynamics, conducting polymers as biomaterials, tissue bioreactor design, and cochlear implant electrodes. Dr. Serban Peteu's research interest is in biosensors, where he has advanced methods to detect metal ions or monitor nitro-oxidative stress in biological fluids. Both electrochemical and optochemical sensing have been investigated, furthermore the response being enhanced via hybrid organic-inorganic nano-architectures. Present work involves nanowire based bio-catalytic interfaces for electrochemical and field-effect sensors. Projects include: semiconductor based lancet type biosensors, electroactive polymers soft actuators, bioreactors designed and fabricated for vaccine research and for water remediation, other equipment and devices to improve the quality of life. Dr. Sub Reddy (C.Chem. MRSC) obtained his first class degree in Chemistry from the University of Manchester. He received his Ph.D. in Membrane-based Electrochemical Biosensing from the same University (1996). His post-doctoral research interests have included the development of quartz crystal-based biosensors, operating in the liquid phase (University of Wales, Bangor; 1994-1997) and the development of application-specific odour sensors (UMIST, Manchester; 1997-1998). Dr. Reddy is, at present, Senior Lecturer in Applied Analytical Chemistry in the Faculty of Health and Medical Sciences at the University of Surrey. Current research interests include the development of smart, permselective and biocompatible molecular imprinted polymers and membrane materials for the sensor/sample interface and the advancement of smart materials-based electrochemical, quartz crystal and optical sensors for medical, food and environmental applications. He is particularly interested in developing hydrogel-based molecularly imprinted polymers (HydroMIPs) for the determination of protein markers and other biomarkers and construction of biosensors.