Development de V.E.A. Russo

Development: Genetics, Epigenetics and Environmental Regulation

V.E.A. Russo

D.J. Cove

L.G. Edgar

R. Jaenisch

F. Salamini

en Limba Engleză Paperback – 23 aug 2014

Studies of selected model organisms have led to a greatly improved understanding not only of the molecular events which take place during development under the control of specific sets of genes, but also of epigenetic and environmental influences on these processes. This book gives an overview of all three of these levels and their relative importance, and as such will give the reader a clear picture of one of the most exciting areas of current biological research.

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Section 1 Microbial Systems, Both Prokaryote and Eukaryote.- 1 Virus Assembly and Morphogenesis.- 2 Spatial and Temporal Control of Gene Expression in Prokaryotes.- 3 Multicellular Development in the Myxobacteria Myxococcus xanthus and Stigmatella aurantiaca.- 4 Cell Type Determination in Yeast.- 5 Genetic and Environmental Influence on Development of the Filamentous Fungus Neurospora crassa.- 6 Cell-Cell Communication in Dictyostelium.- 7 The Cell Division Cycle in Aspergillus nidulans.- Section 2 Plants.- 8 Flowering Plant Embryogenesis.- 9 Root Development in Arabidopsis.- 10 Leaf Development.- 11 Floral Development: Genetic Views and Molecular News.- 12 Genetic Control of Endosperm Development.- 13 Environmental Light Signals and the Development of Arabidopsis.- 14 Plant-Microorganism Symbiosis.- Section 3 Animals.- 15 Caenorhabditis elegans: Embryonic Axis Formation; Signalling in Early Development.- 16 Cell Fate Determination in Caenorhabditis elegans.- 17 Morphogenesis and Organogenesis in Caenorhabditis elegans.- 18 The Regulation of Cell and Growth Cone Migrations During the Development of Caenorhabditis elegans.- 19 Formation of Embryonic Axes and Blastoderm Pattern in Drosophila.- 20 Early Neurogenesis in Drosophila.- 21 Drosophila: Imaginal Disk Development: Patterning the Adult Fly.- 22 Insertional Mutagenesis in Zebrafish.- 23 Spatial and Temporal Control of Maternal Message Utilization.- 24 DNA Methylation.- 25 X-Chromosome Inactivation.- 26 Genomic Imprinting: its Role in Development and Disease.- 27 Myogenesis.- 28 Neurotrophins in Development of the Nervous System.- 29 Olfactory Receptor Gene Regulation.- 30 Genetically Modified Mice as Tools for Cancer Research.- 31 Circadian Timing in Animals.- 32 Polarity in Biological Systems.

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The last 10 years have shown a dramatic revolution in our understanding of development, particularly at the level of molecular genetics, and the profound importance of epigenetic and environmental regulation has been recognized only recently. Development: Genetics, Epigenetics and Environmental Regulation describes the results of this revolution. It is written in a clear way and includes many informative figures. This textbook is intended for students who want a current overview and introduction to specific areas of developmental biology and for researchers who are interested in a summary of developments beyond their individual research interests. Most of the organisms currently being studied are covered, including viruses, bacteria, yeast, Neurospora, Aspergillus, Dictyostelium, Arabidopsis, maize, snapdragon, C. elegans, Drosophila, zebrafish, mouse, hamster, and humans. The subjects discussed range from self-assembly to spatial and temporal gene regulation, from cell type determination to cell-cell communication, and from environmental regulation to genetic imprinting.