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Disease-Modifying Targets in Neurodegenerative Disorders: Paving the Way for Disease-Modifying Therapies

Editat de Veerle Baekelandt, Evy Lobbestael
en Limba Engleză Hardback – apr 2017
Disease-Modifying Targets in Neurodegenerative Disorders: Paving the Way for Disease-Modifying Therapies examines specific neurodegenerative disorders in comprehensive chapters written by experts in the respective fields. Each chapter contains a summary of the disease management field, subsequently elaborating on the molecular mechanisms and promising new targets for disease-modifying therapies.
This overview is ideal for neuroscientists, biomedical researchers, medical doctors, and caregivers, not only providing readers with a summary of the way patients are treated today, but also offering a glance at the future of neurodegenerative disorder treatment.


  • Provides a comprehensive overview of how key proteins in neurodegenerative disorders can be used as targets to modify disease progress
  • Summarizes how patients are treated today, providing a glance at future disease management
  • Includes intelligible and informative information that is perfect for non-specialists, medical practitioners, and scientists
  • Written and peer reviewed by outstanding scientists in their respective fields
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Specificații

ISBN-13: 9780128051207
ISBN-10: 0128051205
Pagini: 320
Dimensiuni: 191 x 235 x 23 mm
Greutate: 0.76 kg
Editura: ELSEVIER SCIENCE

Cuprins

1. The multitude of therapeutic targets in neurodegenerative proteinopathies
2. Synuclein misfolding as a therapeutic target
3. Neuroinflammation as a therapeutic target in neurodegenerative diseases
4A. Stem cells in neurodegeneration: mind the gap
4B. The potential of stem cells in tackling neurodegenerative diseases
5. Preclinical models of Alzheimer’s disease for identification and preclinical validation of therapeutic targets: from fine-tuning strategies for validated targets to new venues for therapy
6. Parkinson’s disease
7. Lewy body dementia
8. Frontotemporal dementia
9. From huntingtin gene to Huntington’s disease-altering strategies
10. Amyotrophic lateral sclerosis: mechanisms and therapeutic strategies