Disseminated intravascular coagulation is a devastating syndrome characterised by the systemic activation of widespread activation of the coagulation cascade and thrombosis, which may result in severe bleeding and may lead to organ failure. Recent studies have shown that the incidence of DIC is decreasing, especially in men. Despite the improvements in health care delivery, the morbidity and mortality due to DIC remains very high. This book provides an important timely update on the clinical manifestations, important risk factors, and treatment strategies for DIC, and provides in-depth information on pathophysiological aspects and various diagnostic scores used to diagnose DIC.