In today's strategic leadership environment, rarely is the Bible considered as a resource to provide insights for leaders to make effective decisions that can be used to craft policy and strategy. Can the Bible provide relevant guidance today among the national leadership who have a propensity to adopt a more secular and humanistic approach in making strategic decisions? This paper examines the strategic decisions, actions and policies of some notable current U.S. historical events to determine if Biblical principles have any correlation to their decision-making process and outcomes.