Dosage Form Design Considerations: Volume I: Advances in Pharmaceutical Product Development and Research
Rakesh Kumar Tekadeen Limba Engleză Hardback – 26 iul 2018
- Examines the history and recent developments in drug dosage forms for pharmaceutical sciences
- Focuses on physicochemical aspects, prefomulation solid state properties and polymorphism
- Contains extensive references for further discovery and learning that are appropriate for advanced undergraduates, graduate students and those interested in drug dosage design
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Specificații
ISBN-13: 9780128144237
ISBN-10: 0128144238
Pagini: 820
Dimensiuni: 191 x 235 x 54 mm
Greutate: 1.95 kg
Editura: ELSEVIER SCIENCE
Seria Advances in Pharmaceutical Product Development and Research
ISBN-10: 0128144238
Pagini: 820
Dimensiuni: 191 x 235 x 54 mm
Greutate: 1.95 kg
Editura: ELSEVIER SCIENCE
Seria Advances in Pharmaceutical Product Development and Research
Public țintă
Researchers and postgraduate students in the field of Pharmaceutics. Also appropriate for those in the pharmaceutical industry, scientists from chemical engineering, and those in drug discovery and development.Cuprins
1. Preformulation in drug research and pharmaceutical product development
2. Physicochemical aspects to be considered in Pharmaceutical Product Development
3. Role of physicochemical parameters on drug absorption and their Implications in Pharmaceutical Product Development
4. Physiologic Factors Related to Drug Absorption
5. Physico-chemical, pharmaceutical and biological considerations in GIT Absorption of drugs
6. Influence of Drug Properties and Routes of Drug Administration on the design of controlled release systems
7. Drug stability and degradation studies
8. First pass metabolism considerations in Pharmaceutical Product Development
9. Dissolution profile considerations during Pharmaceutical Product Development
10. Drug disposition considerations in Pharmaceutical Product Development
11. Protein and tissue binding: Implication on pharmacokinetic parameters
12. Preformulation studies of drug substances, proteins and peptides: Role in drug discovery and Pharmaceutical Product Development
13. Role of salt selection in drug discovery and development
14. Drug Complexation: Implications in drug solubilization and oral bioavailability enhancement
15. Solubility and solubilization approaches in Pharmaceutical Product Development
16. Rheology and its implications on performance of liquid dosage forms
17. Micromeritics in Pharmaceutical Product Development
18. Four stages in Pharmaceutical Product Development – Preformulation – Prototype development - Biological aspects - Scale up studies – Commercialization
19. Scale up studies in Pharmaceutical Product Development
20. Manipulation of physiological processes for Pharmaceutical Product Development
21. Impact of pharmaceutical product Quality on Clinical Efficacy
22. Formulation additives used in Pharmaceutical Products: Emphasis on regulatory perspectives and GRAS
2. Physicochemical aspects to be considered in Pharmaceutical Product Development
3. Role of physicochemical parameters on drug absorption and their Implications in Pharmaceutical Product Development
4. Physiologic Factors Related to Drug Absorption
5. Physico-chemical, pharmaceutical and biological considerations in GIT Absorption of drugs
6. Influence of Drug Properties and Routes of Drug Administration on the design of controlled release systems
7. Drug stability and degradation studies
8. First pass metabolism considerations in Pharmaceutical Product Development
9. Dissolution profile considerations during Pharmaceutical Product Development
10. Drug disposition considerations in Pharmaceutical Product Development
11. Protein and tissue binding: Implication on pharmacokinetic parameters
12. Preformulation studies of drug substances, proteins and peptides: Role in drug discovery and Pharmaceutical Product Development
13. Role of salt selection in drug discovery and development
14. Drug Complexation: Implications in drug solubilization and oral bioavailability enhancement
15. Solubility and solubilization approaches in Pharmaceutical Product Development
16. Rheology and its implications on performance of liquid dosage forms
17. Micromeritics in Pharmaceutical Product Development
18. Four stages in Pharmaceutical Product Development – Preformulation – Prototype development - Biological aspects - Scale up studies – Commercialization
19. Scale up studies in Pharmaceutical Product Development
20. Manipulation of physiological processes for Pharmaceutical Product Development
21. Impact of pharmaceutical product Quality on Clinical Efficacy
22. Formulation additives used in Pharmaceutical Products: Emphasis on regulatory perspectives and GRAS