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Drug Research and Drug Development in the 21st Century: Science and Ethics de H. P. Wolff

Drug Research and Drug Development in the 21st Century: Science and Ethics: Bayer AG Centenary Symposium

Editat de H. P. Wolff, A. Fleckenstein, Egon O. Philipp
en Limba Engleză Paperback – 3 iul 1989
Distinguished scientists and members of the medicalprofession discuss the research and development of safe andsuitable drugs for the long-term treatment of chronicdiseases. The book provides an up-to-date survey on newinsights and technologies - as well as ethicalconsiderations - , since traditional means and methods ofdrug research and drug development may no longer suffice tomeet the challenges of the next century.
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Specificații

ISBN-13: 9783540509615
ISBN-10: 3540509615
Pagini: 324
Ilustrații: XII, 310 p. 14 illus.
Dimensiuni: 170 x 244 x 17 mm
Greutate: 0.52 kg
Editura: Springer Berlin, Heidelberg
Colecția Springer
Seria Bayer AG Centenary Symposium

Locul publicării:Berlin, Heidelberg, Germany

Public țintă

Research

Cuprins

History and Philosophy of Bayer Pharmaceutical Research.- Science, Responsibility, and Society.- Opening Remarks.- Message of Greeting.- I. Unresolved Problems of Chronic Diseases.- Demographic and Epidemiologic Trends Today.- Atherosclerosis and Coronary Heart Disease.- Rheumatoid Arthritis: A Modell of Chronic Inflammation.- Alzheimer’s Disease.- Obstructive Lung Disease.- Biological Approaches to Cancer Therapy.- Challenges and Obstacles hi Clinical Evaluations of Therapy.- Problems, Pitfalls, and Opportunities in Long-term Randomized Trials.- The Impact of Clinical Trials on Clinical Practice.- Panel Discussion I: Cost Effectiveness of Drug Development and Health Economics.- II. Advanced Technologies, Scientific Achievements.- Receptors and Messengers.- Low Density Lipoproteins and Hypercholesterolemia.- Leukotrienes in Airways and Blood Vessels.- Drug Design.- Opening Remarks.- Thoughts About Gene Regulation and Mammalian Development.- Protein Crystallography and Drug Design.- Applying Engineering Principles to the Design of Cellular Biology.- Analytical Pathophysiology and Biochemistry.- Opening Remarks.- Neurotransmitters in the Brain.- Mechanisms of Cancer Metastasis.- Panel Discussion II: Objectives of Basic Research and Predictive Value Preclinical Testing.- The Patient as a Subject to Medical Research.- Ethics of Drug Research and Drug Development.- The Functions of Ethical Committees.- Reduction of Risk to Patients Through Optimized Planning of Clinical Drug Development.- The Quality of Life of Hypertensive Patients in Long-term Studies.- Panel Discussion III: Who is Concerned with Patient Welfare in Research?.- Concluding Remarks.