The effectiveness of hand hygiene was determined by using water alone, carex soap, dettol, imperial leather and hibiscrub as the washing agents while veltia, mitsubishi, dyson, air blow and continuous rolling towel as the hand drying agents in this study.The hands were deliberately inoculated with swab from nostrils and gloves put on for 1 hour to allow the inoculums to be established. While the test (left) hand was washed and dried with selected washing and drying agents, the right hand (reference/control)remained gloved. Both hands (un-gloved)were inoculated on nutrient agar and incubated at 37oC. The colony forming units were Gram stained and biochemical tests done. There was significant difference in test (washed and dried) compared to untreated right hand