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Eosinophil Ultrastructure: Atlas of Eosinophil Cell Biology and Pathology

Autor Rossana C.N. Melo, Ann M. Dvorak, Peter F. Weller
en Limba Engleză Hardback – 12 iul 2022
Eosinophil Ultrastructure: Atlas of Eosinophil Cell Biology and Pathology entirely focuses on eosinophils and their functional roles in inflammation, host defense, and normal homeostatic activities. The book explores the ultrastructure of human eosinophils, highlighting biological processes observed under normal, experimental, and pathological conditions.
Created to fill a void in the eosinophil literature, the book includes an extensive array of electron microscopic images that illustrate the diversity of eosinophil morphology. While the atlas is a learning and teaching tool, it is mainly a helpful  resource for researchers to identify distinguishing features and structural changes that arise during studies of human eosinophils.
The book also covers the ultrastructure of mouse eosinophils under normal and activation conditions and in the context of representative diseases.


  • Gives guidelines to understand the human eosinophils in studies focused on structural biology, cellular immunology, innate and adaptive immunity, immune responses to pathogens, immunopathology, and inflammatory responses
  • Provides a core of essential knowledge to identify both immature and mature eosinophils
  • Comprises a representative compilation of the eosinophil ultrastructure during biological processes, such as activation and degranulation, mostly under experimental conditions
  • Highlights eosinophil biological processes found in vivo during human diseases, thus providing a link between basic science and clinical aspects
  • Helps identify distinguishing features and structural changes that arise during studies of human eosinophils after isolation from body fluids, while in cultures, or biopsies
  • Explains the ultrastructural organization of mature and immature mouse eosinophils, highlighting the similarities/differences between them and human eosinophils
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Specificații

ISBN-13: 9780323994132
ISBN-10: 032399413X
Pagini: 518
Dimensiuni: 216 x 276 x 32 mm
Greutate: 1.63 kg
Editura: ELSEVIER SCIENCE

Public țintă

researchers in  structural biology, cellular immunology, innate and adaptive immunity, immune responses to pathogens, immunopathology, and inflammatory responses.

Cuprins

SECTION I - THE CELL BIOLOGY OF HUMAN EOSINOPHILS 1. Introduction 2. Mature Eosinophils – General Morphology 3. Eosinophils as Secretory Cells 4. Eosinophil Activation 5. Subcellular Localization of Immune Mediators and other Proteins 6. Eosinophil Cell Death 7. Immature Eosinophils
SECTION II - EOSINOPHILS IN HUMAN DISEASES 8. Eosinophil-associated diseases
SECTION III - THE CELL BIOLOGY OF MOUSE EOSINOPHILS 9. Ultrastructure of Mouse Eosinophils