Epilepsy is a chronic brain disease characterized by a long-lasting predisposition to generate seizures and by neurobiological, neuropsychological, social and psychiatric consequences. Our study focused on the epidemio-clinical profile of patients followed for epilepsy at the Neuropsychopathological Center of Kinshasa from 2017 to 2020.Thus, we conducted a retrospective and descriptive study on 47 epilepsy cases selected on the basis of a non-probabilistic convenience survey. Pre-existing departmental data were used for collection. The analysis was done in Epi info 2020 software.Epilepsies represent a heterogeneous group of diseases that can start from the neonatal period to old age, with variable etiology, clinical form and prognosis.