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Essential Pharmacokinetics: A Primer for Pharmaceutical Scientists

Autor Thorsteinn Loftsson
en Limba Engleză Paperback – 31 mar 2015
Essential Pharmacokinetics: A Primer for Pharmaceutical Scientists is an introduction to the concepts of pharmacokinetics intended for graduate students and new researchers working in the pharmaceutical sciences. This book describes the mathematics used in the mammillary model as well as the application of pharmacokinetics to pharmaceutical product development, and is useful as both a self-study and classroom resource. Content coverage includes detailed discussions of common models and important pharmacokinetic concepts such as biological half-life, clearance, excretion, multiple dosage regimens and more. Numerous equations, practical examples and figures are incorporated to clearly illustrate the theoretical background of pharmacokinetic behavior of drugs and excipients.

  • Shows how to apply basic pharmacokinetic methods to evaluate drugs, excipients and drug products
  • Uses guided practice questions, mathematical concepts and real-world examples for self-assessment and retention purposes
  • Illustrates how to write and evaluate drug registration files
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Specificații

ISBN-13: 9780128014110
ISBN-10: 0128014113
Pagini: 178
Ilustrații: 70 illustrations
Dimensiuni: 152 x 229 x 10 mm
Greutate: 0.27 kg
Editura: ELSEVIER SCIENCE

Public țintă

Intended for graduate students and pharmaceutical scientists involved in self-study of the topic or tutored classes in pharmacokinetics, specifically those in non-clinical health-related sciences such as pharmaceutics, drug formulation and medicinal chemistry.

Cuprins

Preface
Chapter 1 - IntroductionChapter 2 – Basic Concepts of PharmacokineticsChapter 3 - Physicochemical Properties and PharmacokineticsChapter 4 - Drug Pharmacokinetics After Alternative Routes of AdministrationChapter 5 - Pharmacologic Response and Drug Dosage AdjustmentsChapter 6 - The Effect of Food and Exipients on Drug PharmacokineticsChapter 7 - Practice Problems
Appendix I: Answers to Problems in Chapter 7Appexndix II: Symbols and Abbreviations

Recenzii

"...an excellent primer on basic pharmacokinetic concepts, with numerous equations, practice problems, and illustrations for students and new researchers in the pharmaceutical sciences. Score: 99 - 5 Stars" --Doody's
"...a valuable introductory reference book...By the end of the book, the reader should have a good grasp of the components of pharmacokinetics." --The Pharmaceutical Journal