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Estrogen Action, Selective Estrogen Receptor Modulators and Women's Health

Editat de V. Craig Jordan
en Limba Engleză Hardback – 26 mai 2013
Presents the evolution of the authors' ideas about estrogen action and its modulation by a fresh group of drugs called SERMs (Selective Estrogen Receptor Modulators). This title presents a journey over years of discovery and success in advancing women's health, with the prospect of improved medicinal chemistry for the future.
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Specificații

ISBN-13: 9781848169579
ISBN-10: 1848169574
Pagini: 507
Dimensiuni: 150 x 229 x 28 mm
Greutate: 0.93 kg
Editura: Imperial College Press

Cuprins

Centennial Article Cancer Research 2009. A Century of Deciphering the Control Mechanisms of Sex Steroid Action in Breast and Prostate Cancer: The Origins of Targeted Therapy and Chemoprevention (V C Jordan); Diethylstilbestrol: The Pioneering Cancer Treatment and Tragedy in Reproductive Endocrinology (J Lewis-Wambi & V C Jordan); Contraception and Women's Health (V D Castracane & V C Jordan); Hormone Replacement Therapy and Women's Health (J Eng-Wong et al.); Induction of Ovulation by Non-Steroidal Antiestrogens (I Obiorah & V C Jordan); Clues About Estrogen and Antiestrogen Action from X-ray Crystallography (G Greene & V C Jordan); Co-Regulator Activity and Their Role in Selective Estrogen Receptor Modulator Action (C D Chien et al.); Role of Estrogen in Familial Breast Cancer (E Rosen & C Isaacs); An Advance with Aromatase Inhibitors (S Chumsri et al.); Adjuvant Antihormone Therapy (A Howell & V C Jordan); Pharmacogenomics of Tamoxifen (H Brauch & V C Jordan); Antihormone Drug Resistance (R Clarke & V C Jordan); Novel Selective Estrogen Receptor Modulators (S Sengupta & V C Jordan); Chemoprevention and Breast Cancer (T Powles et al.); Selective Androgen Receptor Modulators (C C Coss & J T Dalton); Emerging Principle: Selective Nuclear Receptor Modulators (P Fan & V Craig Jordan); Appendix 1: Scientific Survival Suggestions; Appendix 2: Decades of Discovery; Appendix 3: The "Tamoxifen Team" over a 30-year Period: An Account of Students Obtaining a PhD Degree (or MD as a Medical Science Researcher in the British System for Medical Doctors).