This book reviews the various methods in primary prevention of dental caries using evidence based practice methods. The evidence that oral treatment is effective comes from vast extensive and high quality database. The systematic incorporation of new high-quality information together with clinical judgments and personal experience has improved treatment results, reduced the variation in outcomes, and has given the patients more satisfying options. Improvements in traditional clinical decision making, can improve the opportunity for achieving successful results patients decision making is also enhanced when clear choices and realistic estimates of treatment predictability are provided. One of the key principles associated with making good clinical decisions is the need to be scientifically accurate so that unintentional and or hidden sources of bias are most inadvertently allowed to influence the decision process. The process of inductive reasoning which is most common approach used by clinicians, has great potential for erroneous conclusions because it does not normally include the explicit determination of harm. Evidence based dentistry is aimed for all dental practitioners.