​Research-based spin-off companies are a special subgroup of new technology-based ventures and play an important role for innovation and economic development. Executive teams of academic spin-offs face several challenges in building up sustainable and profitable ventures, because they often lack managerial and entrepreneurial skills. Based on a quantitative analysis of 193 German spin-offs RigoTietz examines the relationships between executive team characteristics, strategic decision making, and firm performance. The study contributes to the entrepreneurship and strategic management literature and has practical implications for entrepreneurs and managers, policymakers and practitioners of start-up initiatives and technology transfer organisations.