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Extracellular Mitochondria in Health and Disease: Translational and Applied Bioenergetics

Editat de Carla Lopes, Paulo César da Silva Pinheiro
en Limba Engleză Paperback – oct 2025
Extracellular Mitochondria in Health and Disease covers this new and significant area of research, shedding light on their roles in intercellular communication and disease pathology. These tiny powerhouses, traditionally known for their intracellular functions, are now recognized for their extracellular activities that impact various physiological and pathological processes. The book delves into a range of topics, including cellular mechanisms of mitochondrial transfer, metabolic signaling, and the crosstalk between extracellular vesicles and mitochondria. It serves as a comprehensive guide for scientists, researchers, and students eager to explore these novel findings and their potential implications.

Other sections examine the roles of extracellular mitochondria in immune regulation and inflammation, neurodegeneration and neuroprotection, and their therapeutic potential. By bridging gaps in existing literature, this resource offers up-to-date research and discoveries, providing valuable insights into how extracellular mitochondria could revolutionize medical advancements and improve patient outcomes.

  • Describes cellular mechanisms of mitochondrial transfer and metabolic signaling
  • Discusses extracellular mitochondria in health and disease
  • Explains extracellular mitochondria in immune regulation and inflammation
  • Explores therapeutic potential of extracellular mitochondria
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Specificații

ISBN-13: 9780443292835
ISBN-10: 0443292833
Pagini: 200
Dimensiuni: 191 x 235 mm
Editura: ELSEVIER SCIENCE
Seria Translational and Applied Bioenergetics


Cuprins

1. General introduction
2. Cellular mechanisms of mitochondrial transfer and metabolic signaling
3. Modern techniques for studying extracellular mitochondria
4. Cell-free human mtDNA; A promising disease biomarker
5. Interplay between extracellular vesicles and mitochondria
6. Extracellular mitochondria: Dual roles in neurodegeneration and neuroprotection
7. Extracellular mitochondria and their influence in eye pathologies
8. Extracellular mitochondria in immune regulation and inflammatory diseases
9. Therapeutic potential of extracellular mitochondria: applications and challenges
10. Conclusions and future perspectives