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Fast Release Rabeprazole Sodium Tablet Using Acid-buffer Technology

Autor Alpesh D. Patel, Girish Patel, Natvarlal Patel
en Limba Engleză Paperback – 18 apr 2012
The present invention is aimed to formulate the "non-enteric" formulation of immediate release rabeprazole sodium tablet using acid-buffer technology. The formulation comprising the core tablet containing rabeprazole sodium compression coated with buffer containing super disintegrant. The coat formulation disintegrates fast which provide the higher pH environment then the core formulation gives drug release so degradation of rabeprazole sodium can prevent. From the above perception, the invention is aimed: 1.To study the pH stability of rabeprazole sodium in at different pH medium. 2.To select the proper buffer combination for better basic environment. 3.To formulate the fast release compression coated tablet of rabeprazole sodium. 4.To optimize the formulation using suitable experimental design.
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Specificații

ISBN-13: 9783848485291
ISBN-10: 384848529X
Pagini: 104
Dimensiuni: 152 x 229 x 6 mm
Greutate: 0.16 kg
Editura: LAP LAMBERT ACADEMIC PUBLISHING AG & CO KG
Colecția LAP Lambert Academic Publishing

Notă biografică

Mr. Alpesh D Patel as a assistant professor in BMCPER, Modasa. I have complete my M Pharma in SKPCPER, Kherva. I am pursuing PhD in HNGU, Patan.