Fear and Anxiety de Steven E. Hyman

Fear and Anxiety: The Science of Mental Health

Steven E. Hyman

First published in 2001. This is Volume 10 of ten of a series on the science of Mental Health. Originally published in 2001, this study looks at fear and anxiety. During the past decade there has been substantial progress in the understanding of one emotion in particular: fear. There are descriptions of some of the clinical syndromes followed by sections on epidemiology, genetic and environmental risk factors, and natural history (course of illness). Because anxiety disorders so often co-occur with other mental disorders, there is a section devoted to this issue. The volume also includes an article on the evolutionary psychology of anxiety disorders and a long section on brain and behavior that, among other issues, illustrates current attempts to use new insights into fear circuitry in the brain to help investigate the pathogenesis of anxiety disorders. The volume ends with a section on treatment. In some sections there are articles on panic disorder, PTSD, GAD, social anxiety disorder, and, where appropriate, childhood anxiety disorders (which are not always readily separated into their adult forms). Because simple phobias cause relatively little harm or impairment compared with the other anxiety disorders, they are little discussed.

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Cuprins

Introduction. Description: 2 Phenomenology and Course of Generalized Anxiety Disorder 9 Social Phobia: Review of a Neglected Anxiety Disorder. Epidemiology: 17 The Cross-National Epidemiology of Panic Disorder 22 Posttraumatic Stress Disorder in the National Co morbidity Survey 35 Impairment in Pure and Comorbid Generalized Anxiety Disorder and Major Depression at 12 Months in Two National Surveys 45 Social Phobia Subtypes in the National Co morbidity Survey. Genes and Environment: 53 Patterns of Psychopathology and Dysfunction in High-Risk Children of Parents with Panic Disorder and Major Depression 63 Vulnerability Factors among Children at Risk for Anxiety Disorders. Natural History: 76 Early Childhood Predictors of Adult Anxiety Disorders 82 The Long-Term Course of Panic Disorder and Its Predictors 88 Prospective Study of Posttraumatic Stress Disorder and Depression following Trauma Co-occurrence of Anxiety Disorders and Other Illnesses: 97 Comorbidity and Familial Aggregation of Alcoholism and Anxiety Disorders 113 Comorbidity of Anxiety and Unipolar Mood Disorders 150 Prevalence of Anxiety Disorders and Their Comorbidity with Mood and Addictive Disorders Evolution: 155 Fear and Fitness: An Evolutionary Analysis of Anxiety Disorders Brain and Behavior: 170 A Modern Learning Theory Perspective on the Etiology of Panic Disorder 199 Brain Systems Mediating Aversive Conditioning: An Event-Related fMRI Study 211 The Effects of Early Rearing Environment on the Development of GABAA and Central Benzodiazepine Receptor Levels and Novelty Induced Fearfulness in the Rat 223 The Neuroanatomical and Neurochemical Basis of Conditioned Fear 242 The Amygdala Modulates Prefromal Cortex Activity Relative to Conditioned Fear 245 Neuroanatomical Hypotheses of Panic Disorder, Revised 259 Emotion Circuits in the Brain 289 Activation of the Left Amygdala to a Cognitive Representation of Fear Contents VlJ Treatment 295 Molecular and Neuronal Substrate for the Selective Attenuation of Anxiety 305 Fluvoxamine for the Treatment of Anxiety Disorders in Children and Adolescents The Research Unit on Pediatric Psychopharmacology Anxiety Study Group 309 Psychiatric Reaction Patterns to Imipramine 316 Cognitive-Behavioral Therapy, Imipramine, or Their Combination for Panic Disorder: A Randomized Controlled Trial 323 Multi center, Double-Blind Comparison of Sertraline and Placebo in the Treatment of Posttraumatic Stress Disorder 331 Psychosocial Treatments for Posttraumatic Stress Disorder: A Review 340 Paroxetine Treatment of Generalized Social Phobia: A Randomized,Double, Blind, Placebo-Controlled Study