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Features, Transmission, Detection, and Case Studies in COVID-19

Editat de Rajkumar Rajendram, Victor R. Preedy, Vinood Patel
en Limba Engleză Hardback – 19 iul 2024
Features, Transmission, Detection, and Case Studies in COVID-19 examines the effects of the virus on the body, as well as its transmission and clinical profile. This volume begins with an introduction to the virus and its pathogenesis, transmission, and avoidance, followed by sections on pulmonary and cardiovascular effects, obesity, diabetes, the liver, detection issues, and biomarkers. Vaccines and treatment are also discussed. Specific case studies covered include hypoxia, acute kidney injury, pneumonia, and neurological effects. This volume is relevant for all clinicians and scientists working to ensure the best outcomes for patients with COVID-19.

  • Discusses COVID-19 biology, including pathogenesis and transmission
  • Describes systemic issues caused by COVID-19, including cardiovascular effects and loss of taste and smell
  • Outlines detection methods, biomarkers associated with severity, and disease outcomes
  • Features individual chapter introductions, summaries, and case studies to provide comprehensive descriptions of COVID-19 symptoms and effects
  • Contains chapters with key facts, dictionary of terms, summary points, applications to other areas pertinent to each chapter, and policies and procedures
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Specificații

ISBN-13: 9780323956468
ISBN-10: 0323956467
Pagini: 694
Dimensiuni: 216 x 276 mm
Editura: ELSEVIER SCIENCE

Cuprins

Section A: SARS-CoV-2 and COVID-19: Introductory chapters and setting the scene

1. Coronavirus disease 2019 (COVID-19) pandemic in context: Systemic effects

2. Early warning of SARS-CoV-2 infection

3. Mobile phones and their use to study dynamics of the COVID-19 pandemic

Section B: Structure, transmission and avoidance

4. Cis regulatory elements: A novel communication route between the host cell and the SARS-CoV-2 genome

5. SARS-CoV-2 ORF8: Structure, evolution, molecular function, and its contribution to the
pathogenicity of the virus

6. SARS-CoV-2 spike protein binding ligands and its application in COVID-19 therapeutics

7. SARS-CoV-2 bulldozes the autophagy pathway and unhinges mitochondrial quality control
thereby driving neurodegeneration—A hypothesis

8. The Omicron variant of SARS-CoV-2

9. Monitoring SARS-CoV-2 spread in hospitals

10. Computational analysis of mutations in SARS-CoV-2 variants spike protein and protein
interactions

11. Airborne transmission of SARS-CoV-2

12. Reducing transmission of SARS-CoV-2 with face masks: Its potential protective effects

13. Digital twin of ventilation system against COVID-19 transmission and infection risk

14. Pets and SARS-CoV-2: What is their role in the epidemiology of the disease?

15. SARS-CoV-2 transmission in dental practice

16. SARS-CoV-2 compared with influenza and respiratory syncytial virus in terms of vertical
transmission

17. Reducing droplets and aerosols in the surgical setting and applications to the COVID-19
pandemic

18. SARS-CoV motion dynamics: Linking in droplet size

19. Ventilation and airborne particles in classrooms: Implications for the COVID-19 pandemic

20. Indoor transmission of the SARS-CoV-2 virus through aerosols emitted by e-cigarettes

Section C: Impact and effects

21. The Impact of COVID-19 on first responders

22. COVID-19 and suspected drug-induced liver injury

23. Pulmonary fibrosis in COVID-19

24. The effect of SARS-CoV-2 infection on cancer: Clinical correlation and
potential pathological mechanism

25. Severe SARS-CoV-2, plateletendothelium interactions, and cardiovascular injury

26. Cardiometabolic syndrome and COVID-19: Pathophysiological aspects

27. COVID-19 and type 1 and 2 diabetes: An overview

28. COVID-19 and older adults: An overview

29. COVID-19 and male fertility

30. COVID-19 and obesity: An overview

Section D: Treatments, strategies, and vaccines

31. COVD-19 vaccines and their impact: An overview

32. Exploring the promise of COVID-19 vaccines: A review of preclinical studies

33. Drugs actively being investigated for use in COVID-19

34. The biology of neutralizing antibody therapy with REGEN-COV

35. The intensive care unit and percutaneous tracheostomy in patients with coronavirus disease
2019

36. Cardiac effects of drugs and vaccines used to treat and prevent COVID-19

37. COVID-19 pandemic and isolation: Impact on sleep

38. Strategies in the COVID-19 pandemic: Disinfection of gloved hands

39. In silico studies on established antivirals on SARS-CoV-2 RNAdependent RNA polymerase

40. The COVID-19 cytokine storm and its immunomodulatory treatment

41. Safety and efficacy of nebulization for reducing the intensity of viral load and clinical manifestations in patients with COVID-19

Section E: Detection and biomarkers

42. Bronchoalveolar lavage (BAL) and use in detection of SARS-CoV-2

43. SARS-CoV-2 testing and vaccination among people who use drugs

44. Homocysteine as a biomarker in COVID-19

45. Assessment of smell and taste in COVID-19

46. S-gene analysis: RT-PCR and Sanger sequencing applied to SARS-CoV-2 virus

47. False-negative results in screening for SARS-CoV-2

48. Sample pooling and SARS-CoV-2 assays

49. Biomarkers of invasive mechanical ventilation in obesity and metabolic syndrome in patients
with COVID-19

Section F: Case studies with mini review

50. Hypoxia and heart-lung interactions in COVID-19: The significance of right heart dysfunction and shunt

51. Ulnar nerve dysfunction as COVID-19 sequelae

52. Case study: Coronavirus disease 2019 and acute kidney injury

53. Case study: The detection and treatment of a pneumothorax in a patient with coronavirus disease 2019 pneumonia

54. Proposal and demonstration of a survey method for the prevention of airborne transmission: Case studies in healthcare and welfare facilities

Section G: Resources

55. Recommended resources for the features, transmission, and detection of coronavirus disease
2019 (COVID-19)