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Formulation of Fast Dispersible Tablet of Fexofenadine HCl

Autor Arpitkumar Shah, Mukesh Patel, Natvarlal Patel
en Limba Engleză Paperback – 26 iun 2012
The purpose of this research was to formulate tasteless complexes of Fexofenadine Hydrochloride with Kyron-134 and to formulate tasteless complex into fast-Dispersible tablets (FDT) for the treatment of allergic rhinitis & chronic idiopathic urticaria. Drug release from FDT in salivary pH was insufficient to impart bitter taste. Complete drug release was observed at gastric pH. The studies indicate that the formulation was taste masked drug can be formulated in to FDT with view to enhance patient compliance & to obtain faster onset action of the drug which would be advantageous in comparison to the currently available conventional forms. Formulations D-5 was found to be palatable with in vitro disintegration time of 20 s Dissolution studies showed complete release of D-5 within 30 min.
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Specificații

ISBN-13: 9783659156489
ISBN-10: 3659156485
Pagini: 152
Dimensiuni: 152 x 229 x 9 mm
Greutate: 0.23 kg
Editura: LAP LAMBERT ACADEMIC PUBLISHING AG & CO KG
Colecția LAP Lambert Academic Publishing

Notă biografică

Mr. Arpitkumar Shah has obtained his M. Pharm degree in Pharmaceutics from Shri B. M. Shah college of pharmaceutical education and research, Modasa in 2012 from Gujarat Technological University. He is the author with several articles published in international journals.