Locked in a confrontational stance lasting more than 3 decades, the United States and Iran have failed repeatedly to transform their hostile relationship. The ongoing nuclear talks, however, offer better prospects of not only addressing Iran's nuclear program challenges, but also developing a mutually beneficial strategic relationship between the United States and Iran in the long term. Why are these prospects better today? According to Mr. Roman Muzalevsky, the coming to power of new presidential administrations in both countries, the additional sanctions under the Barack Obama administration, game-changing regional trends, as well as U.S.-Iranian economic and security cooperation imperatives, have all facilitated an interim nuclear deal, prompting talks of a promising start in U.S.-Iranian ties that, if cultivated, could turn into a strategic detente by 2030."