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Functional Groups in Biochemistry: Tailored Chemistry in Biological Contexts

Autor Anthony Serianni
en Limba Engleză Paperback – iun 2025
Functional Groups in Biochemistry: Tailored Chemistry in Biological Contexts includes detailed mechanisms of reactions, focusing on functional groups and their chemical/biochemical properties that determine the biological functions of macromolecules, a connection often overlooked or under-emphasized in standard textbooks. The book provides a deeper understanding of the governing principles of biochemical reactions, as well as how key chemical and biochemical reactions are thought to occur at the atomic/molecular level. With an emphasis on common themes that govern biochemical reactivity, this book fills the gap between organic/bioorganic chemistry and biochemistry texts.


  • Fills the gap between organic/bioorganic chemistry and biochemistry texts
  • Illustrates how key functional groups in biochemistry dictate behaviors in proteins, nucleic acids, or polysaccharides
  • Focuses on functional groups and their chemical/biochemical properties that determine the biological functions of macromolecules
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Specificații

ISBN-13: 9780443139000
ISBN-10: 0443139008
Pagini: 300
Dimensiuni: 152 x 229 mm
Editura: ELSEVIER SCIENCE

Cuprins

Introduction and General Principles

1
(a) Hydroxyl R–OH
(b) Thiol R–SH

2
(a) Ether R1–O–R2
(b) Thioether R1–S–R2

3
(a) Disulfide R1–S–S–R2
(b) Peroxide R–O–O–H
R1–O–O–R2

4
(a) Carboxyl R–COOH
(b) Carboxyester R1–C(=O)–OR2
(c) Imidate R1–C(=NH)–OR2
(d) Thioester R1–C(=O)–SR2
(e) Phosphoester R1–O–PO3H2
R1–O–P(O2H)–R2
R1–O–P(O)(OR2)(OR3)
(f) Sulfoester R1–O–SO2OH
R1–O–SO2–O–R2

5
(a) Aldehyde R–CHO
(b) Carbonyl R1–C(=O)–R2
(c) Imine R–CH(=NH)
R1–C(=NH)–R2

6
(a) Ketoacid R–C(=O)–COOH
(b) Ketoacid R–C(=O)–CH2–COOH
R1–C(=O)–CHR2–COOH
R1–C(=O)–CR2R3–COOH

7
(a) Amine R1R2NH
R1R2R3N
R1R2R3R4N+
(b) Amide R–C(=O)–NH2
R1–C(=O)–NHR2
R1–C(=O)–NR1R2
(c) Amidine R1–C(=NH)–NH2

8
(a) Phosphoanhydride R–O–P(O)(OH)–O–P(O)(OH)2
R1–O–P(O)(OH)–O–P(O)(OH)–OR2
(b) Mixed Anhydride R–C(=O)–O–P(=O)O2H2
R1–C(=O)–O–P(=O)(OR2)(OH)

9
(a) Hemiacetal R1–O–CHR2–OH
(b) Acetal R1–O–CHR2–OR3
(c) Hemiketal R1–O–CR2R3–OH
(d) Ketal R1–O–CR2R3–OR4

Concluding Remarks
References