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Functional Groups in Biochemistry: Tailored Chemistry in Biological Contexts

Autor Anthony Serianni
en Limba Engleză Paperback – iun 2025
Functional Groups in Biochemistry: Tailored Chemistry in Biological Contexts includes detailed mechanisms of reactions, focusing on functional groups and their chemical/biochemical properties that determine the biological functions of macromolecules, a connection often overlooked or under-emphasized in standard textbooks. The book provides a deeper understanding of the governing principles of biochemical reactions, as well as how key chemical and biochemical reactions are thought to occur at the atomic/molecular level. With an emphasis on common themes that govern biochemical reactivity, this book fills the gap between organic/bioorganic chemistry and biochemistry texts.


  • Fills the gap between organic/bioorganic chemistry and biochemistry texts
  • Illustrates how key functional groups in biochemistry dictate behaviors in proteins, nucleic acids, or polysaccharides
  • Focuses on functional groups and their chemical/biochemical properties that determine the biological functions of macromolecules
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Specificații

ISBN-13: 9780443139000
ISBN-10: 0443139008
Pagini: 300
Dimensiuni: 152 x 229 mm
Editura: ELSEVIER SCIENCE

Cuprins

Introduction and General Principles 1 (a) Hydroxyl R–OH (b) Thiol R–SH 2 (a) Ether R1–O–R2 (b) Thioether R1–S–R2 3 (a) Disulfide R1–S–S–R2 (b) Peroxide R–O–O–H R1–O–O–R2 4 (a) Carboxyl R–COOH (b) Carboxyester R1–C(=O)–OR2 (c) Imidate R1–C(=NH)–OR2 (d) Thioester R1–C(=O)–SR2 (e) Phosphoester R1–O–PO3H2 R1–O–P(O2H)–R2 R1–O–P(O)(OR2)(OR3) (f) Sulfoester R1–O–SO2OH R1–O–SO2–O–R2 5 (a) Aldehyde R–CHO (b) Carbonyl R1–C(=O)–R2 (c) Imine R–CH(=NH) R1–C(=NH)–R2 6 (a) Ketoacid R–C(=O)–COOH (b) Ketoacid R–C(=O)–CH2–COOH R1–C(=O)–CHR2–COOH R1–C(=O)–CR2R3–COOH 7 (a) Amine R1R2NH R1R2R3N R1R2R3R4N+ (b) Amide R–C(=O)–NH2 R1–C(=O)–NHR2 R1–C(=O)–NR1R2 (c) Amidine R1–C(=NH)–NH2 8 (a) Phosphoanhydride R–O–P(O)(OH)–O–P(O)(OH)2 R1–O–P(O)(OH)–O–P(O)(OH)–OR2 (b) Mixed Anhydride R–C(=O)–O–P(=O)O2H2 R1–C(=O)–O–P(=O)(OR2)(OH) 9 (a) Hemiacetal R1–O–CHR2–OH (b) Acetal R1–O–CHR2–OR3 (c) Hemiketal R1–O–CR2R3–OH (d) Ketal R1–O–CR2R3–OR4 Concluding Remarks References