The development of fluorescence sensor for detection of cations and anions is a well-established area in modern chemistry because of their immense analytical application in many areas including biology and chemistry. Calix 4]arene based chemosensors have attracted great deal of attention due to their ability to visually sense analytes with high sensitivity as well as fast response time logy and chemistry. Fluorescence technique is widely used for recognition of cations and anions due to its distinct advantages in terms of sensitivity, selectivity, response time and in situ monitoring. Here in this book, we have proposed easy, sensitive and selective method, having low detection limit and fast response fluorescence sensor for recognition of cations and anions.