Hand radiography is usually the first step in the evaluation of arthritis. With hundreds of high-quality images, this work provides a simplified but high-quality diagnostic interpretation of hand radiography, for residents in training and experienced physicians, who wish to improve their knowledge of contemporary rheumatology, according to the rapid progress of treatment using biologic agents and various new diagnostics tools, including MRI and ultrasound. Topics discussed include arthritis in Behcet's disease; adult onset Still's disease; osteonecrosis in lupus; seronegative spondyloarthropathies; gout; and systemic sclerosis.