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Fundamentals of Molecular Diagnostics

Autor David E. Bruns, Edward R. Ashwood, Carl A. Burtis
en Limba Engleză Hardback – 3 iul 2007
This book offers an introduction to the newest, fastest-growing field in laboratory science. Explaining and clarifying the molecular techniques used in diagnostic testing, this text provides both entry-level and advanced information. It covers the principles of molecular biology along with genomes and nucleic acid alterations, techniques and instrumentation, and applications of molecular diagnostics. Written by leading experts, including Patrick Bossuyt, Angela Caliendo, Rossa W.K. Chiu, Kojo S.J. Elenitoba-Johnson, Andrea Ferreira-Gonzalez, Amy Groszbach, Sultan Habeebu, Doris Haverstick, Malek Kamoun, Anthony Killeen, Noriko Kusukawa, Y.M. Dennis Lo, Elaine Lyon, Gwendolyn McMillin, Christopher Price, James Versalovic, Cindy Vnencak-Jones, Victor Weedn, Peter Wilding, Thomas Williams, and Carl Wittwer, this book includes illustrations, tables, and a colorful design to make information easy to find and easy to use.
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Specificații

ISBN-13: 9781416037378
ISBN-10: 1416037373
Pagini: 288
Ilustrații: Approx. 120 illustrations
Dimensiuni: 216 x 276 x 18 mm
Greutate: 0.95 kg
Ediția:1
Editura: Elsevier
Locul publicării:United Kingdom

Cuprins

I. Principles

1.Principles of Molecular Biology

2.Genomes and Nucleic Acid Alterations

II. Techniques and Instrumentation

3.Specimen Collection and Processing

4.Nucleic Acid Isolation

5. Nucleic Acid Techniques

6.Miniaturization: DNA Chips and Devices

7.Design and Operation of a Molecular Diagnostics Laboratory

8.Introduction to Evidence-Based Molecular Diagnostics

III. Applications

9.Inherited Diseases

10.Identity Assessment

11. Molecular Methods in Diagnosis and Monitoring of Infectious Diseases

12. Pharmacogenetics

13. Molecular Genetics in Diagnosis of Human Cancers

IV. Appendix

14.Reference Information

Answers to Review Questions

Glossary