Fused Pyrimidine-Based Drug Discovery: Heterocyclic Drug Discovery
Editat de Raj Kumaren Limba Engleză Paperback – 11 oct 2022
- Covers US FDA approved fused pyrimidine containing drugs and their analyses
- Comprises classification based upon fusion of carbocyclic/heterocyclic rings(s) with a pyrimidine ring, and features their synthetic schemes, approaches and strategies
- Includes new fused-pyrimidine scaffolds, allowing the researcher to predict the mechanisms involved in their synthesis
- Covers fused pyrimidine containing bioactive compounds from the natural sources
- Covers in silico studies of known fused pyrimidines and Structure-Activity Relationship (SAR), which will encourage the development of new or modified existing scaffolds with specific biological activities
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Specificații
ISBN-13: 9780443186165
ISBN-10: 0443186162
Pagini: 378
Dimensiuni: 191 x 235 mm
Greutate: 0.65 kg
Editura: ELSEVIER SCIENCE
Seria Heterocyclic Drug Discovery
ISBN-10: 0443186162
Pagini: 378
Dimensiuni: 191 x 235 mm
Greutate: 0.65 kg
Editura: ELSEVIER SCIENCE
Seria Heterocyclic Drug Discovery
Cuprins
1. Introduction
2. FDA Approved Fused Pyrimidine-Based Drugs
3. Naturally occurring fused pyrimidine derivatives and Medicinal Attributes
4. Five-Membered Ring Fused Pyrimidine-Based Derivatives and Biological Properties
5. FDA approved Five-Membered Ring Fused Pyrimidine-Based Derivatives and Biological Properties
6. Benzene Fused Pyrimidine-Based Derivatives and their Biological Properties
7. Six-Membered Ring (with N, O or S) Fused Pyrimidine-Based Derivatives and Biological Properties
8. FDA approved Six-Membered Ring Fused Pyrimidine-Based Derivatives
9. Seven-Membered Ring Fused Pyrimidine-Based Derivatives and Biological Properties
10. Eight-Membered Fused Pyrimidine Derivatives and Biological Properties
11. Molecular Modeling Studies of Fused Pyrimidine Derivatives at various receptors
2. FDA Approved Fused Pyrimidine-Based Drugs
3. Naturally occurring fused pyrimidine derivatives and Medicinal Attributes
4. Five-Membered Ring Fused Pyrimidine-Based Derivatives and Biological Properties
5. FDA approved Five-Membered Ring Fused Pyrimidine-Based Derivatives and Biological Properties
6. Benzene Fused Pyrimidine-Based Derivatives and their Biological Properties
7. Six-Membered Ring (with N, O or S) Fused Pyrimidine-Based Derivatives and Biological Properties
8. FDA approved Six-Membered Ring Fused Pyrimidine-Based Derivatives
9. Seven-Membered Ring Fused Pyrimidine-Based Derivatives and Biological Properties
10. Eight-Membered Fused Pyrimidine Derivatives and Biological Properties
11. Molecular Modeling Studies of Fused Pyrimidine Derivatives at various receptors