Cantitate/Preț
Produs

Genes, Environment and Alzheimer's Disease

Editat de Orly Lazarov, Giuseppina Tesco
en Limba Engleză Hardback – 15 apr 2016
Genes, Environment and Alzheimer's Disease discusses the role that activities such as exercise can play in cardiovascular health, while also highlighting the fact that the last 10 years have brought great discoveries in the strong environmental component of brain disorders, neurodegeneration, and cognitive decline.
It is now clear that brain insult is an environmental risk factor for AD, while on the other hand, lifestyle components such as exercise and level of education may play a protective role, delaying the onset and/or severity of the disease. Evidence from experiments in rodent models of Alzheimer’s disease contributes major insight into the molecular mechanisms by which the environment plays its role in AD. Additionally, there are diseases related to lifestyle that may lead to AD. This volume reviews new discoveries related to all these factors, serving as a translational tool for clinicians and researchers interested in genetic and environmental risk factors for the disease.


  • Provides the first volume to link genetic and environmental risk factors for Alzheimer’s disease and dementia
  • Aids researchers and clinicians in understanding the basic mechanisms of Alzheimer’s disease and cognitive decline
  • Brings the basic science and clinical perspectives together in a single volume, facilitating translational possibilities
  • Includes a range of molecular to behavioral components assembled into a single volume that creates an excellent resource for basic and clinical neuroscientists
Citește tot Restrânge

Preț: 41918 lei

Preț vechi: 57244 lei
-27% Nou

Puncte Express: 629

Preț estimativ în valută:
8022 8324$ 6705£

Carte tipărită la comandă

Livrare economică 10-24 martie

Preluare comenzi: 021 569.72.76

Specificații

ISBN-13: 9780128028513
ISBN-10: 0128028513
Pagini: 448
Dimensiuni: 152 x 229 x 27 mm
Greutate: 0.84 kg
Editura: ELSEVIER SCIENCE

Public țintă

Basic and clinical neuroscientists working on AD, cognitive decline and dementia

Cuprins

1. What Is Cognition? Molecular Mechanisms of Learning and Memory
  Daniela Puzzo, Jole Fiorito, Rosita Purgatorio, Walter Gulisano, Agostino Palmeri, Ottavio Arancio and Russell Nicholls
2. When Cognitive Decline Becomes Pathology:  From Normal Aging to Alzheimer’s Disease
  Eliezer Masliah and David P. Salmon
3. Adult Neurogenesis and Cognitive Function
  Keri Martinowich and Robert J. Schloesser
SECTION I. Genetic Forms of AD
4. APP and Cognition
  Robert Marr
5. FAD Signaling, PS and Cognition
  Li Gan
SECTION II. Environmental Factors
6. The effect of APOE genotype on amyloid-independent mechanisms
  Guojun Bu
7. Lifestyle and AD
  Orly Lazarov
8. Bace and Cognition
  Giuseppina Tesco
9. Traumatic Brain Injury and Rationale for a Neuropsychological Diagnosis of Diffuse Axonal Injury
  Douglas H. Smith
10. Alzheimer's Disease and the Sleep-Wake Cycle
  Adam W. Bero and Li-Huei Tsai
11. Stroke, Cognitive Function and Alzheimer’s Disease
  Katherine A. Jackman
12. Cerebral innate immunity: a new conceptual framework for Alzheimer’s
  David Gate and Terrence Town
13. Type 2 Diabetes and AD
  Marcelo Bonini