Genome Editing for Neurodegenerative Diseases: From Concept to Clinical Trials
Editat de Sandeep Kumar Singh, Amarish Kumar Yadav, Burkhard Poeggeler, George Perryen Limba Engleză Paperback – 18 oct 2024
- Covers basic mechanisms of genome-editing tools and their therapeutic potential
- Highlights current research progress and the therapeutic strategies to use genome-editing tools against neurodegenerative diseases
- Includes research on genome-editing tool development from the basic concept to clinical trials
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Specificații
ISBN-13: 9780443238260
ISBN-10: 044323826X
Pagini: 260
Dimensiuni: 152 x 229 mm
Greutate: 0.45 kg
Editura: ELSEVIER SCIENCE
ISBN-10: 044323826X
Pagini: 260
Dimensiuni: 152 x 229 mm
Greutate: 0.45 kg
Editura: ELSEVIER SCIENCE
Cuprins
Introduction
Burkhard Poeggeler
1. Therapeutic potential of genome editing tools in neurodegenerative diseases
Ankur Kumar, Nandigam Pardhipa, Sachin G. Swami, Vibha Dwivedi and Anand K. Singh
2. Genetic and molecular basis of neurodegenerative diseases
Sunanda Yogi, Anjali Sangeeth, Anuradha Venkatakrishnan Chimata, Radhika Padma and Amit Singh
3. Genome editing tools: principles, structures, and mechanisms
Rayees Ahmad Naik, Mehak Naseer Mir, Roshni Rajpoot, Sonalika Singh, Kusum Singh and Sandeep Kumar Singh
4. Advances in CRISPER/Cas system and genome editing technologies for the treatment of neurodegenerative diseases
Shailendra Kumar Mishra, Hung-Ming Chang, Ahmad A. Obaid and Sandeep Kumar Singh
5. Use of CRISPR system in genetic screening to detect neurodegenerative disease
Koyel Kar
6. Epigenetic manipulation and gene regulation using the CRISPR/Cas system for neurodegenerative diseases
Josephine Esposto
7. Transgene delivery system: viral, nonviral, and other methods for central nervous system
Bhupender Sahu, Bibhudendu Behera and Umesh Kumar
8. Gene therapies for neurodegenerative disease: current knowledge and challenges
Bhumi Arora, Sakshi Garg, Aditya Shrivastav, Mrinalini Sharma, Bhupender Sahu and Umesh Kumar
9. Gene therapy under clinical trials for neurodegenerative diseases
Bhupender Sahu, Lakshita Tyagi, Prshant Tyagi and Umesh Kumar
10. Clinical challenges and future prospective in use of gene-editing tools as neurotherapeutics
Burkhard Poeggeler
Burkhard Poeggeler
1. Therapeutic potential of genome editing tools in neurodegenerative diseases
Ankur Kumar, Nandigam Pardhipa, Sachin G. Swami, Vibha Dwivedi and Anand K. Singh
2. Genetic and molecular basis of neurodegenerative diseases
Sunanda Yogi, Anjali Sangeeth, Anuradha Venkatakrishnan Chimata, Radhika Padma and Amit Singh
3. Genome editing tools: principles, structures, and mechanisms
Rayees Ahmad Naik, Mehak Naseer Mir, Roshni Rajpoot, Sonalika Singh, Kusum Singh and Sandeep Kumar Singh
4. Advances in CRISPER/Cas system and genome editing technologies for the treatment of neurodegenerative diseases
Shailendra Kumar Mishra, Hung-Ming Chang, Ahmad A. Obaid and Sandeep Kumar Singh
5. Use of CRISPR system in genetic screening to detect neurodegenerative disease
Koyel Kar
6. Epigenetic manipulation and gene regulation using the CRISPR/Cas system for neurodegenerative diseases
Josephine Esposto
7. Transgene delivery system: viral, nonviral, and other methods for central nervous system
Bhupender Sahu, Bibhudendu Behera and Umesh Kumar
8. Gene therapies for neurodegenerative disease: current knowledge and challenges
Bhumi Arora, Sakshi Garg, Aditya Shrivastav, Mrinalini Sharma, Bhupender Sahu and Umesh Kumar
9. Gene therapy under clinical trials for neurodegenerative diseases
Bhupender Sahu, Lakshita Tyagi, Prshant Tyagi and Umesh Kumar
10. Clinical challenges and future prospective in use of gene-editing tools as neurotherapeutics
Burkhard Poeggeler