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Glucocorticoids

Editat de Annemarie C. Pelt
en Limba Engleză Hardback – 9 mar 2011
Glucocorticoids (GC) are a class of steroid hormones that bind to the glucocorticoid receptor, which is present in almost every vertebrate animal cell. GCs are part of the feedback mechanism in the immune system that turns immune activity (inflammation) down. They are therefore used in medicine to treat diseases that are caused by an overactive immune system, such as allergies, asthma, and autoimmune diseases. GCs have many diverse effects, including potentially harmful side effects, and as a result are rarely sold over-the-counter. This book presents topical research from around the globe in the study of glucocorticoids, including the role of genetics in predicting glucocorticoid clinical response; the glucocorticoid receptor signalling in cancer and inflammation; the mechanisms of NO-redox imbalance in glucorticoid hypertension; and GCs in perioperative care.
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Specificații

ISBN-13: 9781617287589
ISBN-10: 161728758X
Pagini: 250
Ilustrații: tables, graphs, diagrams
Dimensiuni: 186 x 262 x 21 mm
Greutate: 0.7 kg
Ediția:New.
Editura: Nova Science Publishers Inc

Cuprins

Preface; Pharmacogenetics of Glucocorticoid Response; The Glucocorticoid Receptor Signaling in Cancer & Inflammation; Glucocorticoids - Age Specific Impact on Mitochondrial Energy Homeostasis; Glucocorticoids, Stress & Cancer: New Insights in Immune System & Tumour Cell Regulations; Hypothalamic Obesity: A Pivotal Role of Endogenous Glucocorticoid; The Role of Nitric Oxide: Redox Imbalance in Glucocorticoid-Induced Hypertension; Glucocorticoids Mediate Drug Resistance: Mechanisms & Its Clinical Impact; Glucocorticoids in Perioperative Care; Glucocorticoid-Mediated Regulation of Tight Junctions in Brain Vascular Endothelium; Glucocorticoid Therapy for Cochlear Injuries: Pharmacology & Evidence from Animal Experiments; Expert Commentary: Glucocorticoids & Exercise Performance in Humans: Current Status; Glucocorticoids, Thymus Function & Sex Hormone in Human Body Growing; Index.