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Goldfrank's Clinical Manual of Toxicologic Emergencies, Second Edition

Autor Robert Hoffman, Sophie Gosselin, Lewis Nelson, Neal Lewin, Mary Howland, Silas W. Smith, Lewis Goldfrank
en Limba Engleză Paperback – 15 dec 2023
Derived from the definitive guide to medical toxicology, this hands-on companion provides accurate information for diagnosing and treating poisoned patients on the spot
After more than a decade on the market, Goldfrank’s Toxicologic Emergencies has established itself as the go-to reference for medical toxicology—and this companion manual distills the most important information into a portable, easy-to-navigate resource.
Goldfrank’s Manual of Toxicologic Emergencies distills critical information into short summaries and synopses, so you can use it to treat patients in clinical settings or for quick review of critical topics. Fully updated to ensure all information is completely current, this new edition is filled with tables, figures, images, and other visuals to make finding the right answers quick and easy. Each chapter is a direct distillation of the corresponding chapter in Goldfrank’s Toxicologic Emergencies.
Whether you’re a medical toxicologist, pharmacist, physician, nurse practitioner, or student, Goldfrank’s Manual of Toxicologic Emergencies provides all the right answers where and when you need them.
Covers the full range of xenobiotics:
  • Includes pharmaceuticals, recreational drugs, and substances of abuse; food and plant toxins; envenomations; household toxins; pesticides and herbicides; rodenticides; metals; poison gases; and environmental toxins
  • Systematically reviews toxicokinetics, pathophysiology, clinical manifestations, diagnostic testing, and management for each xenobiotic
  • Provides "Antidotes in Brief"—at-a-glance guides to specific antidotes and their primary applications
Authoritative answers at your fingertips:
  • How to manage the poisoned or overdosed patient
  • What techniques effectively eliminate toxins
  • Which imaging modalities yield the best results
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Specificații

ISBN-13: 9781260474992
ISBN-10: 1260474992
Pagini: 800
Dimensiuni: 255 x 179 x 31 mm
Greutate: 1.18 kg
Ediția:2
Editura: McGraw Hill Education
Colecția McGraw Hill / Medical
Locul publicării:United States

Cuprins

The table of contents (below) will mirror the main text, both for completeness and ease of cross-referencing.
    Historical Principles and Perspectives
    Toxicologic Misfortunes and Catastrophes in History
    PART A
    THE GENERAL APPROACH TO THE PATIENT
    Initial Evaluation of the Patient: Vital Signs and Toxic Syndromes
    Principles of Managing the Acutely Poisoned or Overdosed Patient
    SC1. Principles of Antidote Stocking
    Decontamination Principles: Prevention of Gastrointestinal Absorption
SC2. Decontamination Principles: Prevention of Dermal, ophthalmic and inhalational Absorption
A1. Activated Charcoal
A2. Whole-Bowel Irrigation and Other Intestinal Evacuants
    Principles and Techniques Applied to Enhance Elimination
    Laboratory Principles
    Principles of Diagnostic Imaging
    Pharmacokinetic and Toxicokinetic Principles
    PART B
    THE FUNDAMENTAL PRINCIPLES OF MEDICALTOXICOLOGY
SECTION I
BIOCHEMICAL AND MOLECULAR CONCEPTS
    Chemical Principles
    Biochemical and Metabolic Principles
    Fluid, Electrolyte, and Acid–Base Principles
    Neurotransmitters and Neuromodulators
    Withdrawal Principles
SECTION II
PATHOPHYSIOLOGIC BASIS: ORGAN SYSTEMS
    Cardiologic Principles I: Electrophysiologic and Electrocardiographic Principles
    Cardiologic Principles II: Hemodynamics
    Dermatologic Principles
SC3. Transdermal Toxicology
    Gastrointestinal Principles
    Genitourinary Principles
    Hematologic Principles
    Hepatic Principles
    Neurologic Principles
    Oncologic Principles
    Ophthalmic Principles
    Otolaryngologic Principles
    Psychiatric Principles
    SC4. patient violence
    Respiratory Principles
    Thermoregulatory Principles
SECTION III
SPECIAL POPULATIONS
    Reproductive and Perinatal Principles
    Pediatric Principles
    Geriatric Principles
    PART C
    THE CLINICAL BASIS OF MEDICAL TOXICOLOGY
    SECTION I
    A. ANALGESICS AND ANTIINFLAMMATORY MEDICATIONS
    Acetaminophen
A3. N-Acetylcysteine
    Colchicine, Podophyllin, and the Vinca Alkaloids
    Nonsteroidal Antiinflammatory Drugs
    Opioids
A4. Opioid antagonists
SC5. Internal Concealment of Xenobiotics
SC6. Harm Reduction for Opioid Overdose
    Salicylates
A5. Sodium bicarbonate
B. Food, Diet, and Nutrition
    Botulism
A6. botulinum antitoxin
    Food Poisoning
    Dieting Xenobiotics and Regimens
    Athletic Performance Enhancers
    Essential Oils
    Plantand Animal-Derived Dietary Supplements
    Vitamins
    Iron
A7. deferoxamine


C. pharmaceuticals
    Pharmaceutical Additives
    Antidiabetics and Hypoglycemics/Antiglycemics
A8. Dextrose(d-Glucose)
A9. octreotide
    Antiepileptics
A10. l-carnitine
    Antihistamines and Decongestants
    A11. physostigmine salicylate
    Chemotherapeutics
    Methotrexate,5-Flourouracil, and Capecitabine
A12. folates :leucovorin (Folinic acid) and Folic Acid
A13. glucarpidase(carboxypeptidase g2)
A14. uridine triacetate
SC7. Inadvertent Intrathecal Administration of Xenobiotics
SC8. Extravasation of Chemotherapeutics
    Antimigraine Medications
    Thyroidand Antithyroid Medications
D. Antimicrobials
    Antibacterials, Antifungals, and Antivirals
    Antimalarials
    Antituberculous Medications
A15. pyridoxine
E. Cardiopulmonary Medications
CASE STUDY 4
    Antidysrhythmics
A16. Magnesium Sulfate
    Antithrombotics
A17. Protein Complex Concentrate and Novel Antithrombotic Antidotes
A18. Vitamin k1
A19. protamine
    β-Adrenergic Antagonists
    A20. Glucagon