Graft vs. Host Disease
Editat de James Ferrara, H. Joachim Deeg, Kenneth R. Cookeen Limba Engleză Paperback – 23 oct 2019
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Specificații
ISBN-13: 9780367393472
ISBN-10: 0367393476
Pagini: 668
Dimensiuni: 178 x 254 mm
Greutate: 1.23 kg
Ediția:3
Editura: CRC Press
Colecția CRC Press
ISBN-10: 0367393476
Pagini: 668
Dimensiuni: 178 x 254 mm
Greutate: 1.23 kg
Ediția:3
Editura: CRC Press
Colecția CRC Press
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Public țintă
Professional ReferenceCuprins
The Pathophysiology of Graft-vs.-Host Disease. Animal Models of Graft-vs.-Host Disease. Graft-vs.-Host Disease as a Th1-Type Process: Regulation by Th2-Type Cells. Role of T-Cell Costimulation and Regulatory Cells in Allogeneic Hematopoietic Cell Transplantation. Chemokines and Graft-vs.-Host Disease. Graft-vs.-Leukemia Effects. The Immune System in Graft-vs.-Host Disease: Target and Effector Organ. Pathology and Pathogenesis of Cutaneous Graft-vs.-Host Disease. Graft-vs.-Host Disease of the Liver. Intestinal Graft-vs.-Host Disease. The Pathophysiology of Lung Injury After Hematopoietic Stem Cell Transplantation. Clinical Spectrum of Acute Graft-vs.-Host Disease. Role of Minor Histocompatibility Antigens in the Development of Graft-vs.-Host Disease and Graft-vs.-Leukemia Reactivity. Advances in Tissue Typing and Their Potential Impact on GVHD Incidence and Severity. Immunosuppression and Immunophilin Ligands: Cyclosporin, Tacrolimus, and Sirolimus. Prophylaxis and Treatments of Acute Graft-vs.-Host Disease. Graft Manipulation to Prevent Graft-vs.-Host Disease. Graft-vs.-Host Disease in Nonmyeloablative Transplant. Adoptive Immunotherapy in Stem Cell Transplantation. Clinical Spectrum and Therapeutic Approaches to Chronic Graft-vs.-Host Disease. Recent Advances and Future Directions.
Notă biografică
James L. Ferrara, Kenneth R. Cooke, H. Joachim Deeg
Descriere
With detailed contributions from more than 40 leading authorities on the topic, this Third Edition comprehensively explores the immunobiology, pathophysiology, and clinical manifestations of graft-versus-host disease (GvHD)-offering sections revealing the most up-to-date research on immune activation and dysregulation, the pathophysiology of target organ damage, and GvHD prevention and treatment.