Recent developments showed that, there are many challenges in environmental awareness and issues of sustainability in the world. Some of the major advantages of this protocol are ambient condition, high yields, short reaction times, simple work-up procedure which will make as an alternative platform for the preparation of thiazines and oxazines under the umbrella of greener and safer processes. We have collected the informational data of thiazine , oxazines and their applications A survey of thiazines and oxazines revealed the moiety have attracted a great deal of interest of medicinal chemist and biochemist and rendered as a lead molecule for designing potential bioactive agents. The Book is divided in to II chapters. Introduction to Thiazines and Oxazines and brief review on biological applications are described in chapter-I. The II chapter deals with green synthesis of Thiazines and Oxazines which will be beneficial to Scientists who are working in Medicinal and pharmaceutical research. AUTHOR