The new guideline, 2nd edition, completely revised and expanded - a standard work for every dialysis centre: Hygiene and quality are closely connected. For this reason, structure and content of the guideline have been adjusted correspondingly. In terms of a QM system, the information provided in this book can be applied for continuous quality improvement. Up-to-date and extended information can be found on: Legal bases, General hygiene, Monitoring and control of permeate and dialysis solutions, Preparation of medical devices, Vascular access management, Home dialysis treatment procedures, Special epidemiological aspects like virus infections and resistant germs. The basic outline of an exemplary hygiene plan is included. Check lists and forms which are important aids in the daily routine have been added.