Handbook of Down Syndrome Research de Dominicus Jelinek

Handbook of Down Syndrome Research

Dominicus Jelinek

Down syndrome is a condition in which extra genetic material causes delays in the way a child develops, both mentally and physically. It affects about 1 in every 800 babies. The physical features and medical problems associated with Down syndrome can vary widely from child to child. In most cases, the child has short and squat body, big neck, macroglossia, hypotonia and handheld fold. While some kids with DS need a lot of medical attention, others lead healthy lives. Though Down syndrome cannot be prevented, it can be detected before a child is born. Furthermore, while some kids with DS have no significant health problems, others may experience a host of medical issues that require extra care. For example, almost half of all children born with DS will have a congenital heart defect. Kids with Down syndrome are also at an increased risk of developing pulmonary hypertension. This book examines this genetic disorder, the detection of possible causes and treatment options for the complications of the disease.

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Cuprins

Preface; Down Syndrome: Genetics, Screening, And Health; Gene Expression Regulation in Down syndrome: Dosage Imbalance Effects at Transcriptome and Proteome Levels; Total (birth + fetal) prevalence, possible causes and prevention of Down Syndrome in Hungary; Social Functioning in Down Syndrome: A Neuropsychological Perspective; The dysfunctional Gastro-intestinal tract in Down syndrome -- congenital or acquired; Infectious diseases of respiratory system during Pregnancy; Mitochondrial Function In Down Syndrome; Informed Choice In Antenatal Screening Of Down's Syndrome; Mother-Child And Father-Child Interaction in Families of Children with Down Syndrome; Ultrasound Screening For Down Syndrome; Dental hygiene, Gingival Modified Index (GMI) and Simplified Oral Hygiene Index (OHIS) in the primary dentition of Down Syndrome Children; Down's syndrome and Dysphagia; Advances In Prenatal Screening for Down Syndrome; Machine Learning applied to Second-trimester Down's Syndrome screening; The influence of oromotor functions and diet consistency on caries experience and growth rate in cerebral palsied individuals; Craniofacial Growth In Patients with Down Syndrome; Hearing loss and middle ear disorders in children with Down syndrome: The need for screening and surveillance systems; The Dental Evidence For Prenatal And Early Postnatal Growth Insults in Down Syndrome; Dealing With Down Syndrome Occurrence Risk; DYRK1A kinase and neuronal cytoskeleton: A new look at pathogenesis of Alzheimer's disease dementia from the perspective of Down Syndrome; Index.