Iron is an essential of human life. This book deals with various aspects related to iron metabolism. Iron has a variety of functions in the body, inclusive of the metabolism of oxygen in a range of biochemical activities. Iron, as heme or in its nonheme form, plays a significant role in key reactions of DNA fusion and energy creation. Low solubility of iron in body fluids and the capability of iron to form toxic fluids in contact with oxygen make iron consumption, use and storage a serious issue. The detection of new metal transporters, receptors and peptides, and detection of innovative cross-interactions between known proteins are now leading to a development in the comprehension of systemic iron metabolism.