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Handbook of Type 1 Diabetes Mellitus

Editat de Leon Aucoin, Tristan Prideux
en Limba Engleză Hardback – 30 iun 2010
Type I diabetes (T1D) is an autoimmune, inflammatory disease, incurable up to date. This book reviews and discusses the progress on environmental triggers and endogenous alarmins linking innate immunity to the pathogenesis of type 1 diabetes. The potential anti-inflammatory treatments for T1D evaluated in several models of the disease are also examined. In addition, while many individual therapies provide partial protection against the development of autoimmune diabetes, recently developed multicomponent vaccine strategies hold promise for restoration of euglycemia and more durable maintenance of immunological homeostasis. This book discusses mechanisms underlying the onset and development of type I diabetes and assesses individual and multicomponent immunosuppression strategies. The T1D associated genes that have been replicated in different populations are also analysed, and whether they could lead to the genetic diagnosis. Other chapters in this book examine the role of physical activity, insulin therapy and dietary management in the treatment of type I diabetes. Aspects of type I diabetes management in children is also reviewed, including current treatment options available, insulin regiments and insulin delivery methods, and structures and mechanism of action of the new insulin analogues.
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Specificații

ISBN-13: 9781607413110
ISBN-10: 1607413116
Pagini: 569
Ilustrații: tables & charts
Dimensiuni: 186 x 261 x 38 mm
Greutate: 1.2 kg
Ediția:New.
Editura: Nova Science Publishers Inc

Cuprins

Preface; Environmental Factors & Concepts in the Induction of Type 1 Diabetes; Novel Approaches for the Treatment of Type 1 Diabetes (T1D): Lessons from Murine Models; Nonconventional Variability Analysis of Cardiovascular Signals in Diabetes Mellitus -- A New Tool to Detect Autonomic Neuropathy; AMPK-S6K1 Signaling Pathway as a Target for Treating Hepatic Insulin Resistance; Environmental Triggers & Endogenous Alarmins Linking Innate Immunity to the Pathogenesis of Type 1 Diabetes; Vaccines for Type 1 Diabetes; A Genetic Diagnosis to Type 1 Diabetes?; Long-Chain Polyunsaturated Fatty Acid Supply in Diabetes Mellitus; Insulin Resistance & Nonalcoholic Fatty Liver Disease (NAFLD)/ Nonalcoholic Steatohepatitis (NASH); Role of Physical Activity in Treatment of Type 1 Diabetes Mellitus; Body Composition & Type 1 Diabetes; Management of Type 1 Diabetes Mellitus in Children; Autoimmune Disorders Associated with Type 1 Diabetes Mellitus: Diagnosis & Implications for Diabetes Control; Diabetes Mellitus: A Disease of Neglect & Business Enterprise; Hope & Challenges for Islet Transplantation in the Treatment of Type 1 Diabetes; Insulin Resistance & Polycystic Ovary Syndrome; Zn2+-Transporter-8: A Dual Role in Diabetes; Changes in the Diabetic Retinopathy in Type 1 Diabetic Patients, after 14 years in a Spanish Population, after the New Diabetes Mellitus Diagnosis Criteria & a More Strict Control of the Patients; The Dilemmas in Differential Diagnosis of Types of Diabetes in Adolescent Patients; Efficacy of Phytotherapeutical Products (Eridiarom(r), Diavit(r)) in Treatment of Type 1 Diabetes Mellitus; New Paradigm: On the Road to Prevent Type 1 Diabetes; Type 1 Diabetes Mellitus & Autoimmune Gastritis; Index.