Harriet Beecher Stowe´s novel Uncle Tom´s Cabin, was one of the most controversial books, published in 1851/52 and put the debate on slavery more strongly in the center of public attention. It had great influence on other writers at that time. This paper deals with the writing and the publishing of Stowe´s masterpiece and the comparison with its most popular stage adaptation by George L. Aiken. Similarities as well as differences will be presented as far as the structure, the characters and the themes are concerned.