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How Not to Study a Disease

Autor Karl Herrup
en Limba Engleză Paperback – 7 mar 2023
"A trade book on Alzheimer's disease--its human face, some insights into its biology, the discoveries that seemed a path to prevention if not cure, 25 years without progress, and a new path forward"--
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Specificații

ISBN-13: 9780262546010
ISBN-10: 0262546019
Pagini: 272
Ilustrații: 28 b&w illustrations
Dimensiuni: 140 x 218 x 20 mm
Greutate: 0.36 kg
Editura: PENGUIN RANDOM HOUSE LLC

Notă biografică

Karl Herrup

Cuprins

Prologue ix
I In the Beginning 1
1 A Layperson's History of Alzheimer's Disease 3
2 A Physician's History of Alzheimer's Disease 23
3 A Scientist's History of Alzheimer's Disease 33
4 Mystery Solved! How Four Discoveries Transformed an Entire Field 53
II What Happened to our Cure? 71
5 Building a Model of Alzheimer's Disease 73
III Double-Edged Swords 97
6 Federal Support of Basic Biomedical Research 99
7 The Pharmaceutical and Biotech Industry 115
8 Testing Our Models: Breaking Bad 131
9 What is Alzheimer's Disease? 149
IV Where Shall We Go From Here? 169
10 A Layperson's Guide to the Biology of Aging 171
11 Building a New Model of Alzheimer's Disease 187
12 Rebalancing our Research Portfolio 207
13 Rebalancing our Institutions 227
14 Final Thoughts 243
Acknowledgments 247
Notes 249
Index 255