Egg is a rich source of all the essential amino acids, minerals and vitamins but it also contains about 200-250mg of cholesterol and is considered to be a major source of dietary cholesterol. Polyherbal preparation containing Emblica officinalis (Amla), Ocimum sanctum (Tulsi), Withania somnifera (Ashwagandha) and Tinospora cordifolia (Giloy) on dietary supplementation showed a significant hypocholestremic effect (P<0.05) in poultry serum and eggs. This preparation can be effectively used for reducing lipid contents in egg yolk for human consumption with the reduced the risk of cardiovascular diseases.