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iGenetics: A Molecular Approach: United States Edition de Peter J. Russell

iGenetics: A Molecular Approach: United States Edition

Autor Peter J. Russell
en Limba Engleză Mixed media product – 6 apr 2005
iGenetics: A Molecular Approach reflects the dynamic nature of modern genetics by emphasizing an experimental, inquiry-based approach with a solid treatment of many research experiments. The text is ideally suited for students who have had some background in biology and chemistry and who are interested in learning the central concepts of genetics.
Problem solving is a major feature of the text and students have the opportunity to apply critical thinking skills to a variety of problems at the end of each chapter. Pedagogical features such as “Principal Points,” at the beginning of each chapter, and “Keynotes,” strategically placed throughout the chapter, are useful learning tools.
The iGenetics CD-ROM and the companion website contain 25 activities and 59 narrated animations, all of which are based on text figures, to help students visualize complex processes and challenging concepts they encounter in the main text.
An intense developmental effort, along with numerous third-party reviews of both text and media, ensure the highest degree of accuracy.
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Specificații

ISBN-13: 9780805346657
ISBN-10: 0805346651
Pagini: 850
Dimensiuni: 216 x 276 mm
Greutate: 1.94 kg
Ediția:2Nouă
Editura: Pearson Education
Colecția Benjamin Cummings
Locul publicării:San Francisco, United States

Cuprins

1. Genetics: An Introduction
2. DNA: The Genetic Material
3. DNA Replication
4. Gene Control of Proteins
5. Gene Expression: Transcription
6. Gene Expression: Translation
7. DNA Mutation, DNA Repair, and Transposable Elements
8. Recombinant DNA Technology
9. Applications of Recombinant DNA Technology
10. Genomics
11. Mendelian Genetics
12. Chromosomal Basis of Inheritance
13. Extensions of Mendelian Genetic Principles
14. Quantitative Genetics
15. Gene Mapping in Eukaryotes
16. Advanced Gene Mapping in Eukaryotes
17. Variation in Chromosome Number and Structure
18. Genetic Analysis of Bacteria and Bacteriophages
19. Regulation Of Gene Expression In Bacteria And Bacteriophages
20. Regulation Of Gene Expression In Eukaryotes
21. Genetic Analysis Of Development
22. Genetics Of Cancer
23. Non-Mendelian Inheritance
24. Population Genetics
25. Molecular Evolution

Notă biografică

Peter J. Russell received his B.S. in Biology from University of Sussex in 1968 and his Ph.D. in Genetics from Cornell University in 1972. He then joined the Biology faculty of Reed College in 1972 where he is currently Professor of Biology. Russell teaches an upper-division genetics and molecular biology lecture/laboratory course, the genetics section of the introductory biology course, an advanced seminar course in yeast virology, and advises senior thesis research students. He is also the author of a number of successful genetics textbooks.
He is currently studying the molecular genetics of the replication of double-stranded (ds) RNA viruses found in budding yeast, Saccharomyces cerevisiae. The research goals are to define in vivo the cis-acting sequences that are required for viral RNA packaging into capsids and for genome replication, and to identify and characterize any yeast gene products required for virus propagation. His earlier research involved Neurospora RNA synthesis and the organization of and regulation of the number of ribosomal RNA genes, and nitrogen metabolism in the pathogenic dimorphic yeast Candida albicans.

Caracteristici

  • The text’s inquiry-based approach engages students in the process of science.
  • Step-by-step examples of problem solving throughout the book represent a wide range of topics and difficulty levels.
  • Pedagogy:
    • Principal Points, appearing at the beginning of each chapter, alert students to key concepts.
    • Keynotes, strategically placed throughout the chapter, summarize important ideas and allow students to check their progress.
    • Summary Sections at the end of each chapter reinforce main ideas.
    • Analytical Approaches to Solving Genetics Problems at the end of each chapter guide students step-by-step through the process of solving genetic problems.
  • Material on recombinant DNA technology and the manipulation of DNA (Chapters 8, 9, and 10) provide students with in-depth coverage.
    • Recombinant DNA Technology (Chapter 8) discusses how to clone DNA, how to make and screen recombinant DNA libraries, how to analyze genes and gene transcripts, how to sequence DNA, and how to amplify DNA using PCR.
    • Applications of Recombinant DNA Technology (Chapter 9) describes how the molecular tools presented in the previous chapter can be applied to study biological processes, test for genetic disease mutations, isolate human genes, fingerprint DNA, develop gene therapy approaches, develop commercial products, and engineer plants genetically.
    • Genomics (Chapter 10) assembles in one chapter an overview of the state-of-the-art analysis of genomes, including how genomes are sequenced completely, a summary of the properties of key genomes that have been sequenced, how genome sequences are analyzed, and how transcriptional and translational profiles can be analyzed for many genes simultaneously.
  • Numerous examples of human genetic disease help students understand the growing importance of molecular medicine.
  • The Genetics Place – This online learning environment offers 25 activities, each with follow-up questions; 59 animations; and practice quizzes that can be graded and the results entered directly into the instructor’s grade book. A syllabus manager and a grade book function are provided as instructor resources. A  complimentary, one-year access code is provided with every new book.
  • iGenetics CD-ROM, packaged with each copy of the text, includes all of the student resources found on the website.
  • Suggested Reading sections contain references to papers that were key to the development of concepts, as well as references to current research in the areas being discussed.

Caracteristici noi

  • A new chapter, Genetic Analysis of Development (Chapter 21), includes the major model organisms: fly, worm, plant, and mouse, with discussions that extend to human systems. There is also treatment of sex determination within the context of development.
  • Extensive coverage of gene mapping is now provided in two chapters. Advanced topics such as tetrad analysis, mitotic recombination, and classical mapping of human genes are segregated into their own chapters for more thorough coverage. In addition, FISH and Radiation Hybrids have been added.
  • Earlier coverage of chromosomal mutations ties the classical sections closer together, helping to wrap up the eukaryotic principles of heredity and adding more human applications and examples of human disease.
  • DNA mutation and repair now follow DNA structure for a more logical flow of information.
  •  An update of genome analysis, with reduced coverage of sequencing, provides a greater focus on what we are learning from analysis.
  • Molecular coverage integrates Mendelian sections where appropriate.
  • The Genetics Placewebsite, www.geneticsplace.com , features two new activities and eight new animations, along with updated quizzes for each chapter.   In addition, all existing activities and animations from the first edition have been heavily reviewed and revised to ensure their accuracy and pedagogical effectiveness.