Immobilized Enzymes in Medicine de Vladimir P. Torchilin

Immobilized Enzymes in Medicine: Progress in Clinical Biochemistry and Medicine, cartea 11

Vladimir P. Torchilin

J. A. Kellen

en Limba Engleză Paperback – 13 dec 2011

The application of immobilized enzymes in medicine is the main objective of this book. The author reviews natural and synthetic carriers for enzyme immobilization, chemistry of enzyme binding, and in-vitro and in-vivo properties of immobilized enzymes. Four chapters are dedicated to clinical use of immobilized enzymes.

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Specificații

ISBN-13: 9783642758232
ISBN-10: 3642758231
Pagini: 220
Ilustrații: VIII, 206 p.
Dimensiuni: 155 x 235 x 12 mm
Greutate: 0.31 kg
Ediția:Softcover reprint of the original 1st ed. 1991
Editura: Springer Berlin, Heidelberg
Colecția Springer
Seria Progress in Clinical Biochemistry and Medicine

Locul publicării:Berlin, Heidelberg, Germany

Cuprins

1 Introduction.- 2 Enzymes in Medicine: Advantages and Disadvantages.- 2.1 Native Enzymes in Therapy and Clinical Analysis.- 2.2 Difficulties Connected with Enzyme Application in Medicine...- 2.3 How the Immobilization can Help.- 3 Immobilization of Therapeutic Enzymes.- 3.1 General Principles of Enzyme Stabilization and Immobilization.- 3.2 The Peculiarities of Enzyme Immobilization for Medical Use. Carriers and Immobilization Methods Required.- 3.3 The Fate of Immobilized Enzymes in the Body.- 3.4 Principal Types of Immobilized Enzymes in Medicine.- 4 Therapeutic Immobilized Enzymes for Parenteral Application.- 4.1 Preparations Intended for Prolonged Circulation in the Body.- 4.2 Insoluble Immobilized Enzymes for Local Application.- 4.3 Immobilization Principles and Drug Targeting.- 5 Immobilized Enzymes for Extracorporeal Application.- 5.1 Immobilized Enzymes in Extracorporeal Systems.- 5.2 Dressing and Drainage Materials Containing Immobilized Enzymes; Films, Ointments and Powders with Immobilized Enzymes in the Treatment of Wounds, Ulcers and Burns.- 6 Immobilized Enzymes in Clinical Analysis.- 6.1 Enzyme Electrodes.- 6.2 Enzyme Immunoassay.- 6.3 Immobilized Bioluminiscent Systems.- 6.4 Reactors with Immobilized Enzymes; Miscellaneous.- 7 Conclusion.- 8 References.