Immortal: Our Cells, DNA, and Bodies
Autor David Goldmanen Limba Engleză Paperback – 30 iun 2021
Immortal: Our Cells, DNA, and Bodies synthesizes what we know about life and death from a genetic, molecular, and cellular perspective, demarcates limits of knowledge, and poses new questions. Award-winning researcher and writer David Goldman examines in-depth three keys to understanding the nature and continuity of life: 1) epigenetic (ephemeral) vs genetic (durable) transgenerational memory; 2) life’s cellular nature, and the ability to make bodies from cells; and 3) the distinction between bodies and persons. Grounded in recent scientific evidence and real-life cases that test our historical understanding of life and death, Goldman probes the nature of molecular continuity in the face of mortal extinction, encompassing how changes to the DNA code can be both long-lasting and transgenerational, and the continuous nature of cellular and molecular information transmission. In tying these themes together, Immortal asks us to apply fresh scientific concepts to examine, for ourselves, the continuity of being in the face of mortality.
- Applies recent genetic, molecular and cellular findings to examine the boundaries between living and non-living, and between person and non-person
- Examines the significance of epigenetic memory and transgenerational inheritance and their uses in molecular and precision medicine
- Written by a thought-leader in genetic and molecular medicine
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Specificații
ISBN-13: 9780323856928
ISBN-10: 0323856926
Pagini: 204
Ilustrații: 20 illustrations (10 in full color)
Dimensiuni: 191 x 235 x 19 mm
Greutate: 0.44 kg
Editura: ELSEVIER SCIENCE
ISBN-10: 0323856926
Pagini: 204
Ilustrații: 20 illustrations (10 in full color)
Dimensiuni: 191 x 235 x 19 mm
Greutate: 0.44 kg
Editura: ELSEVIER SCIENCE
Public țintă
Active researchers, basic and translational scientists, and clinicians in the areas of human genetics, genomics, molecular biology, cell biology, neuroscience, aging, and physiology, internal medicine; bioethicistsclinicians and students of life science, genetics, and medicine; engaged general public
Cuprins
1. Death2. HeLa: The resurrection of Henrietta Lacks3. Persistence of memory4. Hel: Goddess of death and life5. Where self-resides6. Our diploid selves7. Our cellular selves8. From molecule to self9. The ancient divide between molecule and self10. Viruses and other half-life11. Altruism, of cell and self12. Shrines and museums13. Robbing the grave14. Birth15. Anastasia
Recenzii
"This would be an ideal volume for senior capstone courses in science and society courses in liberal arts colleges. He shows how an emergence arises as we shift life science from the molecule to the macromolecule, organelle, gene, chromosome, cell, individual, species, population, and to ecosystems and evolution. He explores the concepts of life and death through folklore, golems, vampires, androids, artificial intelligence, and literature (Franken-stein) as well as raises the inherent contradistinction of "killing the dead." Goldman also explores the problems of personhood as event or process, the struggles of theologians looking for distinctions between soul and self-awareness, and whether sperm and eggs are alive and thus have personhood or lack it. Unlike science, where components and processes are explained as excursions into physical reality, Goldman forces readers to reflect on the status of "half-life," as he designates viruses, prions, and transposons in biology." --The Quarterly Review of Biology
"There is little to which to compare this book. It offers a uniquely modern perspective on age-old questions surrounding life and death, and treads new ground in terms of concepts of cellular mortality and immortality. It is as much moral philosophy as modern science from an author who is capable of writing from both perspectives. It is recommended for the contemplative thinker interested in exploring the meaning of life and death." --©Doody’s Review Service, 2021, Mark F. Sanders, PhD, reviewer, expert opinion
"In his new book, Goldman – not only a first-rank neuroscientist but also a first-rank writer – provides a fresh and fascinating view on the self and the soul, the brain and the body. A must-read for scientists and society." --Katharina Domschke, Chair and Full Professor of Psychiatry, University of Freiburg, Germany
"Reading David Goldman’s Immortal is much like listening to a trusted older brother explaining how life, death, epigenetic research and a myriad of other things all tie together. It's full of color and anecdote but at the same time informed by science and a profound understanding of the subject. The tone is casual but still conveys a quiet sense of magic and wonder," --Rickard L Sjöberg, MD, PhD, Associate Professor of Neurosurgery at Umeå University,
"Dr. David Goldman tackles life’s essential issues – the self, the meaning of life, and the inevitability of death – in this truly evocative and informative volume. Written by one of the nation’s leading genomic scientists, the book combines personal vignettes with cutting edge scientific data to provide empathic yet highly rational perspectives on these complex and vexing questions. A tour de force by a brilliant and illuminating writer." --Anil K. Malhotra, M.D., The Zucker School of Medicine at Hofstra/Northwell
"There is little to which to compare this book. It offers a uniquely modern perspective on age-old questions surrounding life and death, and treads new ground in terms of concepts of cellular mortality and immortality. It is as much moral philosophy as modern science from an author who is capable of writing from both perspectives. It is recommended for the contemplative thinker interested in exploring the meaning of life and death." --©Doody’s Review Service, 2021, Mark F. Sanders, PhD, reviewer, expert opinion
"In his new book, Goldman – not only a first-rank neuroscientist but also a first-rank writer – provides a fresh and fascinating view on the self and the soul, the brain and the body. A must-read for scientists and society." --Katharina Domschke, Chair and Full Professor of Psychiatry, University of Freiburg, Germany
"Reading David Goldman’s Immortal is much like listening to a trusted older brother explaining how life, death, epigenetic research and a myriad of other things all tie together. It's full of color and anecdote but at the same time informed by science and a profound understanding of the subject. The tone is casual but still conveys a quiet sense of magic and wonder," --Rickard L Sjöberg, MD, PhD, Associate Professor of Neurosurgery at Umeå University,
"Dr. David Goldman tackles life’s essential issues – the self, the meaning of life, and the inevitability of death – in this truly evocative and informative volume. Written by one of the nation’s leading genomic scientists, the book combines personal vignettes with cutting edge scientific data to provide empathic yet highly rational perspectives on these complex and vexing questions. A tour de force by a brilliant and illuminating writer." --Anil K. Malhotra, M.D., The Zucker School of Medicine at Hofstra/Northwell