Immunobiology of Proteins and Peptides V: Vaccines Mechanisms, Design, and Applications

Content.- Developments Toward a Recombinant Pertussis Vaccine.- Prospects and Problems in Synthetic Vaccine Development: What did we Learn from the Cholera Toxin System?.- New Concepts in Vaccines for Mucosal Non-Enteric Human Bacterial Pathogens.- Stable Recombinant Avirulent Salmonella Vaccine Strains.- Cytotoxic and Helper T-Lymphocyte Responses to Antibody Recognition Regions on Influenza Virus Hemagglutinin.- Haemophilus b Oligosaccharide-CRM197 and Other Haemophilus b Conjugate Vaccines: A Status Report.- The Application of Molecular Biology to the Development of Novel Vaccines.- Studies on the Clonality of the Antibody Response to a Protein Epitope.- Anti-Idiotype Tumor Vaccines.- A VH Region Synthetic Peptide Induces Antibodies Which Bind Native Immunoglobulins and Augment an Immune Response to Antigen.- Enhancement of Primary and Secondary Immune Responses by Interferon-Gamma.- Interleukin 1 and It’s Synthetic Peptides as Adjuvants for Poorly Immunogenic Vaccines.- Protection Induced by Synthetic Peptides Corresponding to Three Serotypes in Foot and Mouth Disease Virus.- Characterization of a Synthetic Envelope Peptide of SRV-1 and SRV-2 Virus that Specifically Binds Rhesus Anti-SRV-1 and Anti-SRV-2 Neutralizing Antibodies.- Synthetic Peptide Representing a T-Cell Epitope of CRM197 Substitutes as Carrier Molecule in a Haemophilus Influenza Type B (HIB) Conjugate Vaccine.- The Use of Mouse Class II MHC Peptides to Produce Site-Specific Monoclonal Antibodies.- Epitope Mimicry by Anti-Idiotype Sequences in Reverse Orientation.- Vaccine-Containing Biodegradable Microspheres Specifically Enter the Gut-Associated Lymphoid Tissue Following Oral Administration and Induce a Disseminated Mucosal Immune Response.- Potential of Cell-Mediated Immune Responses DirectedAgainst P. Falciparum Sporozoite Peptide Vaccine by Immunomodulators.- Detoxification of Pertussis Toxin by Site-Directed Mutagenesis.- Filamentous Fusion Phage Cloning Vectors for the Study of Epitopes and Design of Vaccines.- Recombinant-Derived Modified-Live Herpesvirus Vaccines.- Advances in Understanding Structure-Function Relationships in Hepatitis B. Virus (HBV) Envelope (ENV) Proteins.- Antigenic Variation During Persistent Lentivirus Infections and its Implications for Vaccine Development.- Antigenic Structure of the Fusion Glycoprotein of Respiratory Syncytial Virus.- SIV Infected Rhesus Macaques: An AIDS Model for Immunoprevention and Immunotherapy.- The Development of Molecular Vaccines Against Malaria Sporozoites.- Developing a Gonococcal Protein I Vaccine.- The Genetics of the Immune Response to Trichinella spiralis Antigens in the Mouse.- Modulation of Antibody Responses by Conjugates of Antigens with Monomethoxypolyethylene Glycol.