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Inborn Errors of Immunity: A Practical Guide

Editat de Asghar Aghamohammadi, Hassan Abolhassani, Nima Rezaei, Reza Yazdani
en Limba Engleză Paperback – 29 ian 2021
Awareness among clinicians about PIDs, which consist of more than 400 different entities, plays an important role in ensuring that patients receive a timely diagnosis. Furthermore, clinicians who are educated about PIDs can give their patients access to optimal management of their condition, thus helping the patient achieve a better quality-of-life and long-term prognosis.
Inborn Errors of Immunity: A Practical Guide provides the most up-to-date information for busy students, nurses, clinical residents, practicing physicians, and even basic researchers. Readers will benefit from a well-structured breakdown of complicated PID diseases, including approaches to their clinical signs/symptoms and immunologic/laboratory findings.


  • Presents valuable contribution of more than 40 expert chapter authors, from top centers spanning five continents, each in a specific PID field
  • Covers various aspects of PID using updated clinical guidelines and standard stepwise pipelines
  • Focuses on the latest developments in the molecular diagnosis and pathogenesis of diseases, with easy explanation and schematic representation of defective signaling pathways
  • Includes dedicated sections for clinical features and immunological tests with carefully-curated figures of PID manifestations, imaging, and histological/pathological illustrations to create the first PID medial-color atlas
  • Summarizes the updated conventional and specific treatments and follow-up notes for different PID diseases
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Specificații

ISBN-13: 9780128210284
ISBN-10: 0128210281
Pagini: 394
Ilustrații: 300 illustrations (150 in full color)
Dimensiuni: 191 x 235 x 23 mm
Greutate: 0.93 kg
Editura: ELSEVIER SCIENCE

Public țintă

General practitioners, hospital clinicians; specialists including pediatricians, infectious disease specialists, allergy and immunology specialists, and rheumatologists.

Cuprins

1. Introduction
2. Immunodeficiencies affecting cellular and humoral immunity
3. Combined immunodeficiencies with associated or syndromic features
4. Predominantly Antibody Deficiencies (PADs)
5. Diseases of immune dysregulation
6. Phagocyte defects
7. Defects in Intrinsic and Innate immunity
8. Auto-inflammatory disorders
9. Complement deficiencies
10. Phenocopies of PID
11. Treatment and Management

Recenzii

"This book provides a broad, comprehensive overview of primary immunodeficiencies (PIDs) and is a useful resource for clinical immunologists and other medical providers. The book is divided into 10 sections with the first 9 sections dedicated to the main classifications of PIDs—combined immunodeficiencies, combined immunodeficiencies with syndromic features, predominantly antibody deficiencies, diseases of immune dysregulation, congenital defects of phagocytes, defects of intrinsic and innate immunity, autoinflammatory diseases, complement deficiencies, and phenocopies of inborn errors of immunity. The last chapters provide a guideline of management and general treatment of patients with PIDs. The layout of this book is such that it is relatively quick and easy to find applicable information of interest. The algorithms and figure+C7s+C6 help aid in the stepwise approach to diagnosis and management of primary immunodeficiencies in a meaningful and cost-effective way. It also includes dedicated sections for clinical features and immunologic tests with well curated figures of PID manifestations, color depictions, imaging, and histologic illustrations. Although the book provides less information on the treatment and management of PIDs, the general guidelines nicely summarize conventional as well as specific treatments and follow-up recommendations. In conclusion, this book successfully simplifies an ever-growing, heterogeneous group of diseases in a way that makes it a useful resource for medical providers. Using this book and the clinical guidelines therein, the reader should be able to identify patients with PID based on their presenting signs and symptoms." --The Annals of Allergy, Asthma and Immunology
"This is definitely a very useful book for the intended audiences. It is easier to read and more engaging than other heavy, detail-oriented books in this area, such as Primary Immunodeficiency Diseases: A Molecular and Genetic Approach, 3rd edition, Ochs et al. (Oxford University Press, 2014), or Primary Immunodeficiency Diseases: Definition, Diagnosis, and Management, 2nd edition, by Rezaei et al. (Springer, 2017), which focus more on the molecular/genetic details and the pathophysiology of the diseases." --© Doody’s Review Service, 2021, Pavadee Poowuttikul, MD(Children's Hospital of Michigan), reviewer, expert opinion
"This book is a fittingly titled, well-written publication. As a lengthy read, Stiehm's utility proves more to be as a comprehensive and informative reference book and guide for clinicians and any other readers interested in immunodeficiency. Readers will be able to easily navigate this well-organized text that provides outstanding details pertaining to immunodeficiencies and their common presentations, diagnostic approaches, and laboratory evaluations for diseases and a focused discussion on immunodeficiency management. Each chapter guides the reader by setting the tone with an overview or introduction, priming the reader for the in-depth text. Furthermore, the reader will find in-color illustrations, pictures, and imaging, which provides a visual aid in helping to solidify the understanding for the rare and complicated conditions discussed. In addition, of great value are the authors' use of tables that serve as an excellent quick reference for a plethora of topics ranging from various syndromes and their associated gene defects to therapeutic uses of vaccines in patients with immunodeficiency." --Annals of Allergy, Asthma and Immunology