The Indigo is an ancient pearl that is said to contain the answer to the problems of all mankind. When it comes to the Grand Museum in Chicago, five students must help discover the secrets hidden within it before it is stolen away forever. A message had been hidden in the pearl, which claims to have been written by Shem, the oldest son of Noah. After the world had become evil again after the great flood, Shem became afraid that the truths of God's love would be forgotten. In ancient Sumerian (cuneiform) Shem wrote a special truth that he didn't want forgotten and hid it in a magnificent giant pearl. He then gave it to the king of Sumer for safe keeping. When the pearl's hiding place is discovered, a greedy professor wants to take the credit and it is up to the heroes of the story to hide a precious artifact from the professor and to discover the secret hidden within. The villain follows them back to their college where they use their "home turf advantage" to evade him and discover the truth.