To sum up, the findings from the present study suggests that both aging and exercise training influence the changes in carbohydrate metabolism in the skeletal muscle fibres that were selected during this program. The differential response of the tissues studied to exercise training, ethanol treatment and combination treatment on carbohydrate metabolic profiles as well as on oxidative and nonoxidative enzyme systems reflects the specific physiological response of these tissues. To conclude, the present findings suggest that 2 months endurance treadmill exercise training with the selected intensity that was adapted may be beneficial in countering the age associated and ethanol induced alterations in carbohydrate metabolic profiles.